A Comparative Study on the Efficacy of Blue Light Emitting Diodes Therapy Versus Targeted Narrow Band UVB in Stable Non-segmental Vitiligo Patients.

NCT ID: NCT07174024

Last Updated: 2025-09-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-01-20

Study Completion Date

2025-08-23

Brief Summary

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A comparative study on the efficacy of blue light emitting diodes therapy versus targeted Narrow band UVB in stable non-segmental vitiligo patients.

Detailed Description

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A comparative study on the efficacy of blue light emitting diodes therapy versus targeted Narrow band UVB in stable non-segmental vitiligo patients.

Conditions

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Vitiligo

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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patients will receive NB-UVB phototherapy sessions on a Randomly selected patch

patients will receive NB-UVB phototherapy sessions on a Randomly selected patch

Group Type ACTIVE_COMPARATOR

Narrow Band UVB Treatment

Intervention Type DEVICE

type of phototherapy

Patients will receive blue light emitting diodes phototherapy on a randomly selected patch

Patients will receive blue light emitting diodes phototherapy on a randomly selected patch

Group Type ACTIVE_COMPARATOR

blue light emitting diode

Intervention Type DEVICE

type of diode

Interventions

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Narrow Band UVB Treatment

type of phototherapy

Intervention Type DEVICE

blue light emitting diode

type of diode

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* All age group.

* Both genders.
* Subjects with stable non-segmental vitiligo (≥2 patches) acral or non-acral patches of diameter ≤ 2cm.

Exclusion Criteria

* Prior treatment with laser therapies for at least 3 months

* Recent exfoliation procedures.
* Recent surgical procedures.
* Poor skin conditions including keloids.
* Hypersensitivity to light ( visible and near-infrared).
* Medications that make users more sensitive to light.
* Anticoagulant and immunosuppressive treatments.
* Gestations or breastfeeding.
* A personal or family history of skin cancer.
* Unstable vitiligo (older lesions have not progressed for the last 1 years and lack of Koebner phenomena ).
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Nahla Maher Mahmoud Mahran

Lecturer of Dermatology

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Cairo University

Giza, Cairo Governorate, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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MS-92-2025

Identifier Type: -

Identifier Source: org_study_id

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