Optimal Treatment Frequency of 308-Nm Excimer Laser for Vitiligo on the Face and Neck

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Study Classification

OBSERVATIONAL

Study Start Date

2005-04-30

Study Completion Date

2006-07-31

Brief Summary

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To determine the optimal treatment frequency of 308-nm excimer laser for vitiligo and identify the key clinical variable(s) associated with the treatment efficiency under the optimal treatment frequency.

Prospective, randomized, comparative study among groups of vitiligo patients treated with 308-nm excimer laser, with the limitation of no follow-up.

Detailed Description

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Vitiligo patients were treated with 308-nm excimer laser for 20 sessions at different frequencies (0.5×, 1.0×, 2.0× and 3.0× weekly). Treatment protocols adapted the dose to the lesions and not to the minimal erythemal dose. Treatment efficacy was blindly evaluated by 2 independent physicians. Re-pigmentation rate was graded on a 6-point scale. The onset of re-pigmentation of vitiligo lesions was evaluated after 5 treatment sessions. The differences between Group 0.5×, 1.0×, 2.0× and 3.0× linking different clinical variables were assessed.

Conditions

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Vitiligo

Keywords

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308-nm excimer laser vitiligo

Study Design

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Study Time Perspective

PROSPECTIVE

Interventions

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308-nm excimer laser

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* older than 2 years, stable vitiliginous patches during the past 3 months with surfaces of at least 4cm2, and an understanding of all information given by signing a written consent form.

Exclusion Criteria

* pregnant or breastfeeding women; personal history of a hypertrophic scar, skin cancer; taking immunosuppressive or photosensitizing drugs and undergoing phototherapy during the past 3 months.

Minimum Eligible Age

2 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Principal Investigators

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gao tianwen, MD,PHD

Role: STUDY_DIRECTOR

Ddepartment of Dermatology

Locations

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Department of dermatology, Xijing Hospital

Xi'an, Shannxi, China

Site Status

Countries

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China

References

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Hofer A, Hassan AS, Legat FJ, Kerl H, Wolf P. Optimal weekly frequency of 308-nm excimer laser treatment in vitiligo patients. Br J Dermatol. 2005 May;152(5):981-5. doi: 10.1111/j.1365-2133.2004.06321.x.

Reference Type RESULT

PMID: 15888156 (View on PubMed)

Other Identifiers

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fmmu200504

Identifier Type: -

Identifier Source: org_study_id