The Value of Using Mini-oral Pulse Steroid Therapy Along With Non Cultured Epidermal Cell Suspension (NCES) in Stable Resistant Vitiligo
NCT ID: NCT06974669
Last Updated: 2025-05-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
NOT_YET_RECRUITING
NA
40 participants
INTERVENTIONAL
2025-05-12
2025-10-01
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Comparison Between Systemic Steroids, Topical Steroids, or Calcineurin Inhibitors With Mini Punch Grafting in Treatment of Stable Non-segmental Vitiligo
NCT04765826
Punch Minigraft Versus Transverse Needling or Combination of Both in Treatment of Non-Segmental Vitiligo
NCT03872804
Effectivness of Topical Tacrolimus Monotherapy in Patients With Vitiligo
NCT03358082
Contribution of Skin Color in Stabilization of Active Cases of Vitiligo by Narrow Band UVB
NCT04030988
Latanoprost Plus NB-UVB Versus Each Alone in Non-segmental Vitiligo: Clinical and Laboratory Evaluation
NCT04811326
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Vitiligo surgery with added mini-oral pulse steroid therapy in the peri-surgical period
this group will receive oral mini-pulse steroids (low-dose dexamethasone: 5mg/week on 2 successive days per week) for 2 weeks prior to NCES and for 4 weeks afterwards
oral steroid-dexamethasone
this study is the first according to the best of our knowledge assessing the value of adding mini oral pulse steroid therapy to non cultured epidermal suspension in treatment of stable acral and difficult to treat vitiligo
non cultured epidermal suspension
this is the best surgical technique for surgical treatment of vitiligo that would be done for both arms
Vitiligo surgery without mini-oral pulse steroid therapy
this group will undergo None cultured epidermal suspension (NCES) without oral mini-pulse steroids.
non cultured epidermal suspension
this is the best surgical technique for surgical treatment of vitiligo that would be done for both arms
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
oral steroid-dexamethasone
this study is the first according to the best of our knowledge assessing the value of adding mini oral pulse steroid therapy to non cultured epidermal suspension in treatment of stable acral and difficult to treat vitiligo
non cultured epidermal suspension
this is the best surgical technique for surgical treatment of vitiligo that would be done for both arms
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Stability for ≥ 1 year
* Age ≥18 years
* Lack of topical treatment for at least 1 month prior to surgery and systemic treatment for at least 3 months prior to surgery.
Exclusion Criteria
* Active vitiligo; new lesions, expansion of old lesions, confetti like lesions, ill-defined edges or koebnerization in \< 1 year
* Age \< 18 years.
* Pregnant females.
* Patients with hypertension, diabetes or tuberculosis
* Topical treatment in the past month and systemic treatment in the past 3 months.
18 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Cairo University
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Rania Mogawer
Lecturer of Dermatology
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Dr. Mogawer, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Dermatology Department, Cairo University Hopsitals
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Dermatology Department, Cairo University Hospitals
Giza, , Egypt
Countries
Review the countries where the study has at least one active or historical site.
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Facility Contacts
Find local site contact details for specific facilities participating in the trial.
Rania Mogawer
Role: primary
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
VS-OMP
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.