Research on the Enhancement of Aerobic Metabolic Energy Supply Capacity by Ischemic Preconditioning.

NCT ID: NCT07170774

Last Updated: 2025-09-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-04-01

Study Completion Date

2024-06-01

Brief Summary

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The purpose of this clinical trial is to investigate whether IPC can improve aerobic capacity during exercise. The primary question it aims to answer is: Does IPC enhance the aerobic capacity of athletes? The researchers will compare IPC (220 mmHg pressure) with a placebo (20 mmHg pressure) to see if different interventions can enhance aerobic capacity and exercise performance.

Participants will:

* Undergo a randomized crossover controlled trial, visiting twice, with a one-week interval between each test.
* Conduct two assessments at the testing site each time, namely a pre-intervention assessment and a post-intervention assessment.
* Record their heart rate, blood pressure, weight, oxygen uptake, Taekwondo-specific performance, and other indicators.

Detailed Description

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Conditions

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Ischemic Preconditioning Aerobic Capacity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

OTHER

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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IPC Trial

220 mmHg

Group Type EXPERIMENTAL

Ischemic Preconditioning

Intervention Type DEVICE

Compression cuff width: 10CM; Compression duration: 5min/5min (ischemia/reperfusion) \*4. 220 mmHg

SHAM Trial

20 mmHg

Group Type PLACEBO_COMPARATOR

Sham

Intervention Type DEVICE

Compression cuff width: 10CM; Compression duration: 5min/5min (compression/relaxation) \*4. 20 mmHg

Interventions

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Ischemic Preconditioning

Compression cuff width: 10CM; Compression duration: 5min/5min (ischemia/reperfusion) \*4. 220 mmHg

Intervention Type DEVICE

Sham

Compression cuff width: 10CM; Compression duration: 5min/5min (compression/relaxation) \*4. 20 mmHg

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* adult male athletes aged 18 years or older;
* taekwondo athletes classified as national second-class or above (having placed in the top three provincial professional taekwondo championships or the top eight national professional taekwondo championships);
* consistent and unified training over the past three months;
* no prior ischemic preconditioning;
* competitive taekwondo athletes.

Exclusion Criteria

* supplementation with creatine;
* acute or chronic illnesses, including anxiety, depression, cardiovascular diseases, and metabolic disorders;
* engaging in vigorous physical activity within 48 hours prior to the experiment;
* consuming alcohol or caffeine within 24 hours before the experiment.
Minimum Eligible Age

18 Years

Maximum Eligible Age

22 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Ziyue Ou

OTHER

Sponsor Role lead

Responsible Party

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Ziyue Ou

Sponsor-Investigator

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Guangzhou Sport University

Guangzhou, , China

Site Status

Countries

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China

References

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Cheng CF, Kuo YH, Hsu WC, Chen C, Pan CH. Local and Remote Ischemic Preconditioning Improves Sprint Interval Exercise Performance in Team Sport Athletes. Int J Environ Res Public Health. 2021 Oct 12;18(20):10653. doi: 10.3390/ijerph182010653.

Reference Type BACKGROUND
PMID: 34682399 (View on PubMed)

Chen Y, Yang J, Muradov O, Li X, Lee JKW, Qiu J. Effect of ischemic preconditioning on maximum accumulated oxygen deficit in 400-meter runners. Eur J Sport Sci. 2023 May;23(5):789-796. doi: 10.1080/17461391.2022.2064769. Epub 2022 Apr 25.

Reference Type BACKGROUND
PMID: 35400298 (View on PubMed)

Caru M, Levesque A, Lalonde F, Curnier D. An overview of ischemic preconditioning in exercise performance: A systematic review. J Sport Health Sci. 2019 Jul;8(4):355-369. doi: 10.1016/j.jshs.2019.01.008. Epub 2019 Jan 23.

Reference Type BACKGROUND
PMID: 31333890 (View on PubMed)

Albuquerque MR, Flor CAG, Ribeiro AIS, Mesquita PHC, Franchini E, Laurentino GC. Effects of Ischemic Preconditioning on Sport-Specific Performance in Highly Trained Taekwondo Athletes. Sports (Basel). 2024 Jun 26;12(7):179. doi: 10.3390/sports12070179.

Reference Type BACKGROUND
PMID: 39058070 (View on PubMed)

Other Identifiers

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2023WCXTD011

Identifier Type: -

Identifier Source: org_study_id

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