Hyperbaric VO2max Study

Study Results

Results available

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Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

PHASE2

Total Enrollment

25 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-02-28

Study Completion Date

2016-05-31

Brief Summary

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This study seeks to examine the effectiveness of training while in a hyperoxic-hyperbaric environment for exercise performance at altitude. Subjects will complete a short, high-intensity interval training (HIT) program inside the hyperbaric chamber.Before and after this training phase, all subjects will be tested for maximum aerobic capacity at a simulated high altitude of 15,000ft in a hypobaric chamber, as well as for molecular markers of mitochondrial oxidative capacity in a skeletal muscle biopsy.

A group of individuals of similar characteristics completing this training program in a normoxic-normobaric environment will serve as a control.

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Detailed Description

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Conditions

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Exercise Training

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Hyperoxic, Hyperbaric

Hyperoxic hyperbaric interval exercise training Six sessions of 30 min.of High-intensity interval training completed on a 3-times a week basis at 1.4 ATA of oxygen in a hyperbaric chamber.

Group Type EXPERIMENTAL

Hyperoxic hyperbaric interval exercise training

Intervention Type PROCEDURE

Six 30-min high-intensity interval training sessions completed 3-times a week while at 1.4 ATA of oxygen in a hyperbaric chamber.

Oxygen

Intervention Type DRUG

Used in Hyperoxic hyperbaric interval exercise training intervention

Normoxic, Normobaric

Normoxic, normobaric, interval exercise training Six sessions of 30 min.of High-intensity interval training completed on a 3-times a week basis.

Group Type SHAM_COMPARATOR

Normoxic, normobaric, interval exercise training

Intervention Type PROCEDURE

Six 30-min high-intensity interval training sessions completed 3-times a week.

Interventions

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Hyperoxic hyperbaric interval exercise training

Six 30-min high-intensity interval training sessions completed 3-times a week while at 1.4 ATA of oxygen in a hyperbaric chamber.

Intervention Type PROCEDURE

Normoxic, normobaric, interval exercise training

Six 30-min high-intensity interval training sessions completed 3-times a week.

Intervention Type PROCEDURE

Oxygen

Used in Hyperoxic hyperbaric interval exercise training intervention

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* healthy, recreationally active or sedentary individuals

Exclusion Criteria

* VO2max \< 35 ml/kg/min - male 30 ml/kg/min - female
* chronic cardiovascular or pulmonary diseases
* history of pneumothorax
* active smoker
* pregnant women
* non-english speaking
* not in full mental capacity
* blind
* sickle cell trait or disease

Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes