Comparison of the Effect of Different Inspiratory Loads on Diaphragmatic Function in Healthy Individuals

NCT ID: NCT07143721

Last Updated: 2025-08-27

Basic Information

• Recruitment Status: ACTIVE_NOT_RECRUITING
• Total Enrollment: 10 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2025-06-30
• Study Completion Date: 2025-11-01

Brief Summary

This pilot study aims to evaluate how the diaphragm responds to different inspiratory muscle training loads using ultrasound in healthy individuals. The observational, cross-sectional research seeks to determine whether ultrasound measurements of diaphragm movement and thickness can more effectively guide load prescription, thereby optimizing the benefits of inspiratory training. Twenty healthy participants, of both sexes, aged 18 to 35 years, will be recruited through outreach at the Faculty of Physiotherapy at the University of Vigo. The assessment will include spirometry, maximum inspiratory pressure (MIP) measurement, and ultrasound evaluations of the diaphragm at various loads (10%, 30%, 50%, and 70% of the MIP). Data will be analyzed to understand how diaphragm mobility, thickness, and contraction velocity vary according to load, with the goal of improving training prescription and adjustment. The study adheres to the ethical principles of the Declaration of Helsinki and ensures strict confidentiality and participant anonymity. The results will contribute to the understanding of non-invasive diaphragm assessment and its role in enhancing respiratory and physical performance.

Conditions

Healthy Volunteers

Study Design

• Observational Model Type: OTHER
• Study Time Perspective: PROSPECTIVE

Study Groups

Healthy adults undergoing inspiratory muscle training at varying intensities

Ultrasound assessment of diaphragm movement and thickness, spirometry, maximum inspiratory pressure measurement, breathing exercises at different load intensities.

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

Healthy adults aged 18 to 35 years

No history of neuromuscular, cardiovascular, respiratory, or musculoskeletal diseases that could limit participation

Not currently on medication affecting muscle function

Willing to provide informed consent

Exclusion Criteria

Pregnant women

Recent thoracic or abdominal trauma (within the last 3 months)

Respiratory symptoms in the last two weeks

Conditions preventing performing forced inspiratory maneuvers

Recent respiratory muscle training (within the last 6 months)

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 35 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University of Vigo

OTHER

Sponsor Role: lead

Responsible Party

Eva María Lantarón Caeiro

principal investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Eva María Lantarón Caeiro L Dra Eva María Lantarón Caeiro, Dra

Role: PRINCIPAL_INVESTIGATOR

Universidad de Vigo

Locations

Facultad de Fisioterapia-Universidade de Vigo

Pontevedra, España, Spain

Countries

Spain

Other Identifiers

Muscle training

Identifier Type: -

Identifier Source: org_study_id