Evaluation of Skeletal Muscle Function Using Ultrasonic Elastography

NCT ID: NCT05805332

Last Updated: 2023-04-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-04-07

Study Completion Date

2024-12-31

Brief Summary

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The goal of observational study is to evaluation of skeletal muscle function in patients with chronic obstructive pulmonary disease before and after lung rehabilitation training using ultrasonic elastography in Chronic Obstructive Pulmonary Disease. The main question it aims to answer are:Evaluation of skeletal muscle function in patients with chronic obstructive pulmonary disease before and after lung rehabilitation training using ultrasonic elastography.

Participants will undergo pulmonary rehabilitation.

Detailed Description

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Conditions

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Chronic Obstructive Pulmonary Disease

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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pulmonary rehabilitation

pulmonary rehabilitation

Intervention Type OTHER

The participants would undergo pulmonary rehabilitation.

Interventions

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pulmonary rehabilitation

The participants would undergo pulmonary rehabilitation.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* The age is between 40-80 years old
* Patients with chronic obstructive pulmonary disease who meet the diagnostic criteria of GOLD guideline(2019)
* There was no acute exacerbation in the past 12 weeks

Exclusion Criteria

* Hypoxemia (oxygen partial pressure is less than 60mmHg or oxygen saturation is less than 88% at rest), or patients who need continuous oxygen inhalation, or patients with any contraindication to exercise test (refer to the American Thoracic Association/American Association of Thoracic Physicians exercise test guidelines)
* Oral glucocorticoids
* Receive long-term oxygen therapy prescription
* Have participated in supervised exercise programs in the past 12 months
* History of other lung diseases, including pneumoconiosis, bronchiectasis, tuberculosis, primary pulmonary hypertension, pulmonary embolism, interstitial lung disease
* Diseases that restrict the active exercise ability of participants or involve skeletal, neuromuscular, cardiovascular or metabolic disorders of muscle activity, such as tumors, diabetes, muscle weakness, etc
Minimum Eligible Age

40 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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China-Japan Friendship Hospital

OTHER

Sponsor Role lead

Responsible Party

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Gang Hou

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Mingming Deng, MD

Role: CONTACT

86 18801336854

Other Identifiers

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2022-NHLHCRF-LX-01-0202-4

Identifier Type: -

Identifier Source: org_study_id

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