Acute Effects of Inspiratory Muscle Training at Different Intensities in Healthy People

NCT ID: NCT03788356

Last Updated: 2019-04-08

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 36 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2019-01-02
• Study Completion Date: 2019-04-04

Brief Summary

At least 30 volunteers will be included in the study. After questioning the demographic and clinical information of the participants, dyspnea perception, respiratory functions, respiratory muscle strength, heart rate variability, arterial stiffness, and blood pressure and physical activity levels will be evaluated. Inspiratory muscle training will be done for 15 minutes with an electronic device. Respiratory training will be applied at three different concentrations with 10%, 30% and 60% of maximal inspiratory pressure. Heart rate variability, arterial stiffness, and blood pressure measurements will be repeated after inspiratory muscle training sessions at different intensities.

Detailed Description

Cardiovascular diseases are the leading cause of mortality in developed and developing countries and constitute a significant morbidity burden for life. Cardiovascular diseases risk factors include obesity, lipid profile, unhealthy diet, sedentary lifestyle, high blood pressure, increased arteriosclerosis.

Although aerobic exercise is recommended as exercise modality to reduce cardiovascular risk, the effects of resistant exercise on cardiovascular health are not clear. In addition, regular aerobic and resistant exercise regulate cardiac autonomic function.

Inspiratory muscle training is a time-efficient, well-tolerated and safe approach for both healthy people and people with chronic diseases. Long-term inspiratory muscle training has been shown to increase respiratory muscle strength and decrease blood pressure in healthy individuals. One-session inspiratory muscle training has been shown to improve autonomic function in smokers and older individuals. However, the effects of different intensities of inspiratory muscle training on blood pressure, autonomic function, and arterial stiffness in healthy young people are not fully understood. For these reasons, the aim of the study is to investigate the acute effects of inspiratory muscle training at different intensities in healthy people.

At least 30 volunteers will be included in the study. After questioning the demographic and clinical information of the participants, dyspnea perception, respiratory functions, respiratory muscle strength, heart rate variability, arterial stiffness, and blood pressure and physical activity levels will be evaluated. Inspiratory muscle training will be done for 15 minutes with an electronic device. Respiratory training will be applied at three different concentrations with 10%, 30% and 60% of maximal inspiratory pressure. Heart rate variability, arterial stiffness, and blood pressure measurements will be repeated after inspiratory muscle training sessions at different intensities.

Conditions

Healthy

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: CROSSOVER
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Diaphragmatic breathing

Diaphragmatic breathing exercise for 15 minutes.

Group Type: EXPERIMENTAL

Diaphragmatic breathing

Intervention Type: OTHER

Diaphragmatic breathing exercise

10% inspiratory muscle training

Inspiratory muscle training at 10% intensity of maximal inspiratory pressure for 15 minutes

Group Type: EXPERIMENTAL

Inspiratory muscle training

Intervention Type: DEVICE

Inspiratory muscle training with a device

30% inspiratory muscle training

Inspiratory muscle training at 30% intensity of maximal inspiratory pressure for 15 minutes

Group Type: EXPERIMENTAL

Inspiratory muscle training

Intervention Type: DEVICE

Inspiratory muscle training with a device

60% inspiratory muscle training

Inspiratory muscle training at 60% intensity of maximal inspiratory pressure for 15 minutes

Group Type: EXPERIMENTAL

Inspiratory muscle training

Intervention Type: DEVICE

Inspiratory muscle training with a device

Interventions

Inspiratory muscle training

Inspiratory muscle training with a device

Intervention Type: DEVICE

Diaphragmatic breathing

Diaphragmatic breathing exercise

Intervention Type: OTHER

Other Intervention Names

Exercise

Eligibility Criteria

Inclusion Criteria

• Healthy People

Exclusion Criteria

• Body mass index (BMI) > 30 kg/m²
• Smoking
• The presence of exercise habit
• Medication use
• Neurological, cardiovascular or respiratory disorders

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 25 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Dokuz Eylul University

OTHER

Sponsor Role: lead

Responsible Party

Buse Ozcan Kahraman

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Dokuz Eylül University

Izmir, , Turkey (Türkiye)

Countries

Turkey (Türkiye)

References

Tanriverdi A, Kahraman BO, Ozsoy I, Ozpelit E, Savci S. Acute effects of inspiratory muscle training at different intensities in healthy young people. Ir J Med Sci. 2021 May;190(2):577-585. doi: 10.1007/s11845-020-02353-w. Epub 2020 Aug 26.

Reference Type: DERIVED

PMID: 32851483 (View on PubMed)

Other Identifiers

2018/14-16

Identifier Type: -

Identifier Source: org_study_id