Investigation of Inspiratory Muscle Training Applied at Different Intensities on Intercostal Muscle Oxygenation

NCT ID: NCT07029074

Last Updated: 2025-12-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

27 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-07-23

Study Completion Date

2026-06-23

Brief Summary

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In this study, it was aimed to investigate the acute effect of inspiratory muscle training of different intensities on intercostal muscle oxygenation in healthy individuals.

Detailed Description

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The functional activity of the respiratory system must be regular and efficient in order to meet the oxygen needs of tissues and organs. The mechanical function of the respiratory system is significantly related to the working capacity of the respiratory muscles. The diaphragm is the primary muscle that provides respiratory functions among the respiratory muscles.The external intercostal muscles help with the inspiration, while the internal intercostal muscles help with the expiration. The basis of inspiratory muscle training is to reduce dyspnea, increase inspiratory muscle function and exercise tolerance. Inspiratory muscle training provides an increase in muscle strength by increasing inspiratory muscle strength, reducing metaboreflex activity and increasing blood flow to the muscles. Training is thought to minimize the effects of activation of inspiratory muscle metaboreflex in both healthy individuals and patients with heart failure. In chronic respiratory patients, forced inspiration effort reduces capillary perfusion of the respiratory muscles, thus increasing the oxygen demand of the muscle. Muscle oxygen saturation shows the oxygen uptake and oxygen consumption of the muscle. It aims to investigate the mechanisms involved in the metaboreflex response to respiratory fatigue in inspiratory muscle training, which severity will acutely reduce it more.

Conditions

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Healthy

Keywords

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muscle oxygenation inspiratory muscle training intercostal muscle

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

This study was designed as a single-blind randomized, placebo-controlled, crossover study.
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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MIP 70% inspiratory muscle training

Individuals participating in the study will be randomly assigned inspiratory muscle training sessions maximal inspiratory pressure of 70% under the supervision of a specialist physiotherapist for 30 minutes.

Group Type EXPERIMENTAL

MIP 70% inspiratory muscle training

Intervention Type OTHER

POWERbreathe Wellness (POWERbreathe International Ltd.., England, UK) device will be used for inspiratory muscle training.

Sham inspiratory muscle training (Maximal inspiratory pressure (MIP) 0%)

Individuals participating in the study will be randomly assigned sham inspiratory muscle training sessions maximal inspiratory pressure of 0% under the supervision of a specialist physiotherapist for 30 minutes.

Group Type EXPERIMENTAL

Sham inspiratory muscle training (MIP 0%)

Intervention Type DEVICE

POWERbreathe Wellness (POWERbreathe International Ltd.., England, UK) device will be used for inspiratory muscle training.

MIP 30% inspiratory muscle training

Individuals participating in the study will be randomly assigned inspiratory muscle training sessions maximal inspiratory pressure of 30% under the supervision of a specialist physiotherapist for 30 minutes.

Group Type EXPERIMENTAL

MIP 30% inspiratory muscle training

Intervention Type DEVICE

POWERbreathe Wellness (POWERbreathe International Ltd.., England, UK) device will be used for inspiratory muscle training.

Interventions

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Sham inspiratory muscle training (MIP 0%)

POWERbreathe Wellness (POWERbreathe International Ltd.., England, UK) device will be used for inspiratory muscle training.

Intervention Type DEVICE

MIP 30% inspiratory muscle training

POWERbreathe Wellness (POWERbreathe International Ltd.., England, UK) device will be used for inspiratory muscle training.

Intervention Type DEVICE

MIP 70% inspiratory muscle training

POWERbreathe Wellness (POWERbreathe International Ltd.., England, UK) device will be used for inspiratory muscle training.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Physically active (doing moderate intensity physical activity for at least 3 days a week for 150 minutes / week)
* Volunteer to participate in the study

Exclusion Criteria

* Healthy individuals with any diagnosed chronic or systemic disease,
* Smoke 10 packs x years or more,
* Pneumonia or any acute infection,
* Psychiatric disorder will excluded in the study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Kirsehir Ahi Evran Universitesi

OTHER

Sponsor Role lead

Responsible Party

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Başak KAVALCI KOL

Principle Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Kırşehir Ahi Evran University, Physical Therapy and Rehabilitation Center, Cardiopulmonary Unit

Kırşehir, , Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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Başak KAVALCI KOL, PhD

Role: CONTACT

Phone: +903862802317

Email: [email protected]

Other Identifiers

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AhiEvranU529

Identifier Type: -

Identifier Source: org_study_id