Study of the Cognitive and Neurophysiological Effects of the Activ4Brain Program for Older Adults
NCT ID: NCT07108413
Last Updated: 2025-08-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
72 participants
INTERVENTIONAL
2024-01-01
2025-03-30
Brief Summary
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This study aims to answer the following questions.
* Does the program Activ4Brain improve cognition in cognitively healthy older adults?
* Does the program Activ4Brain change brain function and body physiology in cognitively healthy older adults?
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Detailed Description
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The primary objective of this study is:
• Evaluation of the efficacy of the Activ4Brain program in improving cognition in older people
Secondary objectives are:
* Evaluation of the impact of the Activ4Brain program on brain and autonomic function and physical health markers
* Evaluation of participants' adherence and retention through attendance rates across all intervention sessions and participation trends over time
* Evaluation of the feasibility of the Activ4Brain program including its acceptability, accessibility, and usability.
Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
SUPPORTIVE_CARE
NONE
Study Groups
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Activ4Brain Group
Participants in this group perform the Activ4Brain program during 3 months
Activ4Brain Program
The Activ4Brain Program consists of 24 sessions, twice a week for 3 months. Participants engage in 50 min exercise sessions of moderate intensity (60-80% of maximal heart rate) including 5 min warm-up, 40 min aerobic exercises, and 5 min cool-down. The warm-up period includes similar body movements as the main part of the exercise and dynamic stretching while the cool down period consists of static stretching. The main part of the exercise session is divided in four blocks. Each block consists of 5 min aerobic exercises and 5 min of cognitive training. Participants are instructed to keep moving, marching in place, while performing the cognitive training tasks to maintain the increased heart rate. Each group class is composed of four participants with as must as possible a narrow age range given the participants' schedule convenience.
Aerobic exercise group
Participants in this group perform an Aerobic Exercise program during 3 months
Aerobic Exercise Program
The Aerobic Exercise Program consists of 24 sessions, twice a week for 3 months. Participants engage in 50 min exercise sessions of moderate intensity (60-80% of maximal heart rate) including 5 min warm-up, 40 min aerobic exercises, and 5 min cool-down. The warm-up period includes similar body movements as the main part of the exercise and dynamic stretching while the cool down period consists of static stretching. The main part of the exercise session consists of a sequence of four different 5 min blocks of aerobic exercise repeated twice. Each block consists of a combination of three different rhythmic movements. Each group class is composed of four participants.
Control group
Participants in this group receive no intervention during the study and are instructed to carry on their daily routines.
No interventions assigned to this group
Interventions
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Activ4Brain Program
The Activ4Brain Program consists of 24 sessions, twice a week for 3 months. Participants engage in 50 min exercise sessions of moderate intensity (60-80% of maximal heart rate) including 5 min warm-up, 40 min aerobic exercises, and 5 min cool-down. The warm-up period includes similar body movements as the main part of the exercise and dynamic stretching while the cool down period consists of static stretching. The main part of the exercise session is divided in four blocks. Each block consists of 5 min aerobic exercises and 5 min of cognitive training. Participants are instructed to keep moving, marching in place, while performing the cognitive training tasks to maintain the increased heart rate. Each group class is composed of four participants with as must as possible a narrow age range given the participants' schedule convenience.
Aerobic Exercise Program
The Aerobic Exercise Program consists of 24 sessions, twice a week for 3 months. Participants engage in 50 min exercise sessions of moderate intensity (60-80% of maximal heart rate) including 5 min warm-up, 40 min aerobic exercises, and 5 min cool-down. The warm-up period includes similar body movements as the main part of the exercise and dynamic stretching while the cool down period consists of static stretching. The main part of the exercise session consists of a sequence of four different 5 min blocks of aerobic exercise repeated twice. Each block consists of a combination of three different rhythmic movements. Each group class is composed of four participants.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Presence of objective cognitive impairment screened with the Addenbroke's Cognitive Examination - Revised, which also incorporates the Mini Mental State Examination, providing a double score
* Presence of high fall risk screened with the Timed Up and Go test (TUG)
* Presence of severe neurological or psychiatric conditions
55 Years
75 Years
ALL
No
Sponsors
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University of Coimbra
OTHER
Responsible Party
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Maria Ribeiro
Principal Investigator
Principal Investigators
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Maria J Ribeiro, PhD
Role: PRINCIPAL_INVESTIGATOR
CIBIT-ICNAS, University of Coimbra, Portugal
Locations
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University of Coimbra
Coimbra, , Portugal
Countries
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Related Links
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social media page of the Activ4Brain program
Other Identifiers
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Activ4Brain
Identifier Type: -
Identifier Source: org_study_id
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