CMR-derived Quantitative Perfusion for Prediction of FFR

NCT ID: NCT07018778

Last Updated: 2025-06-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-07-01

Study Completion Date

2026-09-30

Brief Summary

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Patients will undergo quantitative perfusion assessment in cardiovascular magnetic resonance imaging (dual bolus or dual sequence approach) as well as invasive coronary angiography for assessment of fractional flow reserve (FFR) including assessment of coronary flow reserve (CFR) and microcirculatory resistance (IMR).

Detailed Description

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Conditions

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Chronic Coronary Syndrome

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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CCS patients

Clinical patients referred for ischaemia testing (CMR/coronary angiogram) will undergo the respective counterpart as well so that patients will have undergone both CMR and invasive testing.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* clinical indication for vasodilatator CMR or invasive coronar angiography
* capability to give informed consent

Exclusion Criteria

* general: non-compliance, \<18 years of age, pregnancy
* contraindications for CMR (non-CMR compatible device, chronic kidney disease (eGFR \<30ml/min), allergies (medications)
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Kerckhoff Klinik

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Kerckhoff Klinik

Bad Nauheim, Hesse, Germany

Site Status

Countries

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Germany

Central Contacts

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Sören Jan Backhaus, MD

Role: CONTACT

06032-996-2620

Andreas Rolf, MD

Role: CONTACT

06032-996-2620

Facility Contacts

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Markus Schönburg

Role: primary

Other Identifiers

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AZ 107/24

Identifier Type: -

Identifier Source: org_study_id

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