Comparing Two Eccentric Protocols on Muscle Damage

NCT ID: NCT06992271

Last Updated: 2025-05-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-03-08

Study Completion Date

2025-06-01

Brief Summary

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The purpose of this study will be to test whether a new way of weight training is more effective than typical weight training. The investigators expect that this new way will cause more exercise-induced muscle damage, which helps people build bigger muscles. Another purpose of this study will be to explore perceptions of how muscle soreness impacts participant activities of daily living.

Detailed Description

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Participants will come to the lab for 3 sessions, plus two email follow-up questionnaires.

Session 1 (45 minutes)

* Complete a demographic questionnaire
* Self-assess muscle soreness
* Walk on the treadmill to warm-up
* Maximal voluntary contraction on the chest press
* Two sets of eccentric (lowering) bench press at 75% of max

Session 2 (45 minutes)

* Walk on the treadmill to warm up
* Maximal voluntary contraction on the chest press
* Three sets of 10 eccentric contractions at 75% of max
* Repeat the maximal voluntary contraction on the chest press

Session 2 Follow-up Rate muscle soreness for each of the three days following Session 2 Answer open-ended questions about perceptions of the muscle soreness

Session 3 (45 minutes) Walk on the treadmill to warm up Maximal voluntary contraction on the chest press Three sets of 10 eccentric contractions at 75% of max Repeat the maximal voluntary contraction on the chest press

Session 3 Follow-up Rate muscle soreness for each of the three days following Session 2 Answer open-ended questions about perceptions of the muscle soreness

Conditions

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Eccentric Hypertrophy Muscle Damage

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Crossover design with two groups
Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Fast Eccentric

Participants will perform fast eccentric resistance training

Group Type EXPERIMENTAL

Fast Eccentric

Intervention Type BEHAVIORAL

Resistance training done quickly

Slow eccentric

Participants will perform slow eccentric resistance training

Group Type ACTIVE_COMPARATOR

Slow Eccentric

Intervention Type BEHAVIORAL

Resistance training done slowly

Interventions

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Fast Eccentric

Resistance training done quickly

Intervention Type BEHAVIORAL

Slow Eccentric

Resistance training done slowly

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Sixteen young adults (ages 18-35) will be enrolled in this study.
* In order to be enrolled, they must have completed at least three months of resistance training in the past five years in order to minimize the learning effect and chance of injury.

Exclusion Criteria

* Since regular resistance training reduces the primary outcomes, muscle damage and soreness, individuals who currently participate in chest press resistance training at least once per week will be excluded.
* Individuals who have musculoskeletal injuries in the shoulder, elbow or wrist that preclude pain-free resistance training, or who have underlying uncontrolled cardiovascular complications will also be excluded.
* Women who are pregnant, or may consider becoming pregnant over the subsequent 2 months, will be excluded
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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New York Institute of Technology

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Amerigo Rossi, Ed.D

Role: PRINCIPAL_INVESTIGATOR

New York Institute of Technology

Locations

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NYIT

Old Westbury, New York, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Amerigo Rossi, Ed.D

Role: CONTACT

516 686-3884

Facility Contacts

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Amerigo Rossi, EdD

Role: primary

516-686-3884

Other Identifiers

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BHS-1835

Identifier Type: -

Identifier Source: org_study_id

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