Hypertension, Ethnicity and Exercise Trial

NCT ID: NCT06824805

Last Updated: 2025-02-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-06-01

Study Completion Date

2023-11-30

Brief Summary

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The main aim of this study is to investigate the acute effects of a single bout of isometric handgrip exercise (IHG) and a single bout of aerobic endurance exercise (AEX) on blood pressure, both immediately after exercise and during the subsequent activities of daily living in patients with high-normal to grade 1 hypertension of South-Asian or African descent living in Suriname.

Detailed Description

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Conditions

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Hypertension

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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isometric handgrip exercise

4x2 minutes of isometric handgrip exercise

Group Type ACTIVE_COMPARATOR

Exercise

Intervention Type BEHAVIORAL

aerobic exercise for 30 minutes at 40-60% HRres

control

seated control session

Group Type NO_INTERVENTION

No interventions assigned to this group

Aerobic exercise

aerobic exercise at 40-60% HRres

Group Type EXPERIMENTAL

Exercise

Intervention Type BEHAVIORAL

aerobic exercise for 30 minutes at 40-60% HRres

Interventions

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Exercise

aerobic exercise for 30 minutes at 40-60% HRres

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* • Age 18 - 65 years

* Patients with high- normal BP (SBP: 130 - 139 mmHg or and DBP: 85 - 89 mmHg) or stage I hypertension (SBP: 140 - 159 mmHg or DBP: 90 - 99 mmHg) according to the ESC/ESH guidelines \[15\]
* Asian or African descent
* Do not meet the level of physical activity recommended by the WHO based on self-report \[15\]
* Non-medicated patients or patients using a maximum of 2 antihypertensive drugs

Exclusion Criteria

* • Functional or mental limitation limiting the correct execution of an exercise bout

* History of ischemic stroke, autonomic neuropathy, cardiovascular, renal, or pulmonary disease by self-report
* Diabetes type I or II
* Pregnancy
* The presence of exercise induced signs of myocardial ischemia or complex ventricular arrhythmia during CPET
* Patients using three or more antihypertensive drugs or patients with resistant hypertension
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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KU Leuven

OTHER

Sponsor Role lead

Responsible Party

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Véronique Cornelissen

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Anton De Kom University

Paramaribo, , Suriname

Site Status

Countries

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Suriname

Other Identifiers

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183/2020

Identifier Type: -

Identifier Source: org_study_id

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