Effect of Aerobic Exercise in Patients With Essential Hypertension

NCT ID: NCT05987436

Last Updated: 2023-08-14

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 138 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2017-11-01
• Study Completion Date: 2019-12-01

Brief Summary

The goal of this observational study is to evaluate the effects of a supervised aerobic exercise training program on weight loss, functional capacity, quality of life (QoL), and depression levels in patients with essential hypertension.

Detailed Description

Patients who chose the treatment type according to personal preferences were divided into two groups: Group 1(n:91) exercised for six weeks, five sessions per week under the supervision of a medical doctor in the aerobic exercise laboratory, and group 2(n:47) was advised to maintain dietary habits and physical activity levels. Body weight, serum lipid levels, functional capacity, QoL, and depression level of all the participants were evaluated at baseline and 6 weeks later.

Conditions

Aerobic Exercise; Essential Hypertension

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Group 1

Group 1 exercised for six weeks, involving once per day, five sessions per week under the supervision of a medical doctor, and a nurse in the aerobic exercise laboratory. The aerobic exercise training program lasted six weeks, and patients lived in the hospital for the whole period. Aerobic exercise training was performed on cycle ergometers (Ergoline, ergoselect II 100/200/Reha, Germany) equipped with a computed ergometer and developed to monitor electrocardiography (ECG), heart rhythm, and BP. Each session consisted of a 5-minute warm-up, followed by 50 minutes of aerobic exercise with an intensity of 50% to 70% of heart rate reserve, calculated by Karvonen formula, and ended with a 5-min cool-down period.

Supervised Aerobic Exercise

Intervention Type: OTHER

Group 1 exercised for six weeks, five sessions per week under the supervision of a medical doctor in the aerobic exercise laboratory.

Group 2

The subjects assigned to the control group (Group 2) were advised to maintain dietary habits and physical activity levels and the aerobic exercise program was provided to them after completing the study.

No interventions assigned to this group

Interventions

Supervised Aerobic Exercise

Group 1 exercised for six weeks, five sessions per week under the supervision of a medical doctor in the aerobic exercise laboratory.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Over 18 years of age,
• Absence of concomitant other metabolic and cardiovascular diseases.

Exclusion Criteria

• Having suffered an event of ischaemic heart disease (<6 months),
• Secondary hypertension,
• Hypertrophic obstructive cardiomyopathy,
• Congestive heart failure,
• Uncontrolled cardiac arrhythmia,
• Thyroid dysfunction,
• Diabetes mellitus,
• Symptomatic peripheral arterial occlusive disease,
• Aortic insufficiency or stenosis,
• Pulmonary or heart disease with dyspnoea at small or moderate effort,
• An outbreak of orthopedic problems on hip, knee or ankles, such as arthroplasty, contracture or severe osteoarthritis,
• Using of antidepressant or anxiolytic drugs,
• Pregnancy,
• Cognitive disfunction.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 75 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

TC Erciyes University

OTHER

Sponsor Role: lead

Responsible Party

Hasan Kara

Medical Doctor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Selcuk University Faculty of Medicine

Konya, , Turkey (Türkiye)

Countries

Turkey (Türkiye)

Other Identifiers

HKara2

Identifier Type: -

Identifier Source: org_study_id