Various Procedural Treatment Options for Post-acne Atrophic Scars
NCT ID: NCT06770608
Last Updated: 2025-01-13
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
PHASE2
60 participants
INTERVENTIONAL
2025-01-31
2025-04-30
Brief Summary
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Detailed Description
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OBJECTIVE: "To compare the outcome of microneedling with autologous platelet rich plasma verses microneedling with topical insulin in the treatment of post-acne atrophic scars".
Material \& Methods: This randomized comarative study will be carried out in Outpatient Dermatology Department, Sheikh Zayed Hospital Rahim Yar Khan, Pakistan. Approval of the study has been taken from ethical review committee of the hospital.Data will be collected on prescribed form. Patient will be selected on basis of inclusion \& exclusion criteria. Informed consent will be taken from selected patients before data collection. Study will includes 60 patients which will be divided into 2 groups A \& B, 30 in each group. Group A will receive micro-needling with topical application of 2ml of human actrapid insulin. Group B will receive micro-needling with topical application of 2ml Platelet rich plasma. Face of the patient will be washed after 30 mints and patients will be strictly instructed regarding sun protection at least 1 day after the procedure. Blood glucose level will be checked prior to and 30 mints following procedure.
At monthly interval for total 4 sessions and follow up visit will be after 2 months of last session.Data will be analyzed by SPSS v25.0.
Chi-square test will be applied for qualitative variables and t-test will be used for quantitative variables.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Micro-needling with topical human actrapid insulin group (Group A)
Patients with post-acne atrophic scars will receive micro-needling with topical application of 2ml of human actrapid insulin
micro-needling with topical human actrapid insulin
Micro-needling with topical application of 2ml of human actrapid insulin once monthly for 4 months
Micro-needling with topical Platelet rich plasma(Group B)
Patients with post-acne atrophic scars will receive micro-needling with topical application of 2ml Platelet rich plasma
Micro-needling with topical Platelet rich plasma
Micro-needling with topical application of 2ml Platelet rich plasma once monthly for 4 months
Interventions
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micro-needling with topical human actrapid insulin
Micro-needling with topical application of 2ml of human actrapid insulin once monthly for 4 months
Micro-needling with topical Platelet rich plasma
Micro-needling with topical application of 2ml Platelet rich plasma once monthly for 4 months
Eligibility Criteria
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Inclusion Criteria
* Gender: both male and female
* Type of acne scar: Atrophic acne scar
* Patients not taking prior treatment in last 1-2 months
Exclusion Criteria
* Bleeding disorders
* Platelet count less than 100000
* Hypersensitivity to insulin, PRP
* Keloidal tendency
* Active herpes simples, warts and molluscum contagiosum
* Unrealistic expectations
13 Years
50 Years
ALL
No
Sponsors
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Sheikh Zayed Medical College
OTHER_GOV
Responsible Party
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Mohibullah Zahidi
Post Graduate Resident in Dermatology
Locations
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Sheikh zayed Medical College and Hospital
Rahim Yar Khan, Punjab Province, Pakistan
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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sheikh-ZMC
Identifier Type: -
Identifier Source: org_study_id
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