Comparison Of Outcome Of Microneedling With Autologous PRP Vs Microneedling With Topical Insulin In Treatment Of Post Acne Atrophic Scars.

NCT ID: NCT06002854

Last Updated: 2023-08-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-08-01

Study Completion Date

2023-02-01

Brief Summary

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Microneedling with topical INSULIN is a simple, effective tool for building body's new collagen layers and thus an alternative to all erosive techniques such as lasers, peels. The skin responds to fine punctures with the release of growth factors. 8 It is a safe procedure that can be performed in the office without complications, with a good cost-benefit because it is economically viable without any effect on patient's daily activities. 9

Detailed Description

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Conditions

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ATROPHIC ACNE SCARS

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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GROUP A Microneedling with PRP(platelete rich plasma)

Group Type EXPERIMENTAL

PRP( platelet rich plasma) and Insulin human

Intervention Type DRUG

Microneedling with autologus PRP reduces inflammationin acne scars. Insulin human is a new topical drug which is used nowadays for acne scars as it is more effective in producing collagen formation as well as new blood vessel formation

GROUP B Microneedling with topical INSULIN

Group Type EXPERIMENTAL

PRP( platelet rich plasma) and Insulin human

Intervention Type DRUG

Microneedling with autologus PRP reduces inflammationin acne scars. Insulin human is a new topical drug which is used nowadays for acne scars as it is more effective in producing collagen formation as well as new blood vessel formation

Interventions

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PRP( platelet rich plasma) and Insulin human

Microneedling with autologus PRP reduces inflammationin acne scars. Insulin human is a new topical drug which is used nowadays for acne scars as it is more effective in producing collagen formation as well as new blood vessel formation

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* postacne atrophic scars ≥ 2 on Goodman and Baron's acne scar-grading system
* Either gender.
* Age 20-50 years.

Exclusion Criteria

* lactation and pregnancy
* skin cancers and infection
* photosensitivity like SLE ,XP
* use of RETINOIDS in last 6 months.
Minimum Eligible Age

20 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Jinnah Postgraduate Medical Centre

OTHER_GOV

Sponsor Role lead

Responsible Party

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Nazia Jabeen

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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KHADIJA ASADULLAH, MBBS

Role: PRINCIPAL_INVESTIGATOR

JPMC

FAIZA INAM, FCPS

Role: PRINCIPAL_INVESTIGATOR

JPMC

PARISA SANAWAR, FCPS

Role: PRINCIPAL_INVESTIGATOR

JPMC

Locations

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JPMC

Karachi, Sindh, Pakistan

Site Status

Countries

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Pakistan

Other Identifiers

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NO.F.2-81/2022-GENL/252/JPMC

Identifier Type: -

Identifier Source: org_study_id

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