Comparison of Efficacy of Microneedling With Platelet Rich Plasma Vs Microneedling With Topical Insulin in the Treatment of Acne Scars
NCT ID: NCT06978361
Last Updated: 2025-05-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
116 participants
INTERVENTIONAL
2025-03-01
2025-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Group A , Microneedling with autologous PRP
Patients in group A will undergo microneedling with autologous PRP i.e cleansing of the treatment area with an antiseptic solution will be performed.Topical anesthetic will be applied to the area for 20-30 mins .Approximately 10ml of blood will be drawn into sterile tubes. blood sample will be placed in centrifuge 10-15mins which separates the blood components, allowing for the collection of PRP .Then sterile microneedling device will be used to begin the procedure by adjusting the needle depth according to scar severity.Controlled microinjuries to the skin will be made by moving the device in a systematic pattern over the treatment area .After microneedling ,immediately harvested PRP will be applied to the treated area ,allowing it to penetrate into the microinjuries .Patient will be asked for consideration of aftercare instructions ,including avoiding sun exposure , harsh skincare products and strenuous exercise for few days.
Microneedling with autologous Platelet Rich Plasma
Patients in group A will undergo Microneedling with autologous PRP
Group B , Microneedling with Topical insulin
Patients in group B will undergo microneedling with Topical insulin i.e cleansing of the treatment area with an antiseptic solution will be performed.Topical anesthetic will be applied to the area for 20-30 mins to reduce discomfort during the procedure.Then sterile microneedling device will be used to begin the procedure by adjusting the needle depth according to scar severity.Controlled microinjuries to the skin will be made by moving the device in a systematic pattern over the treatment area .After microneedling Insulin (Regular) will be applied immediately to the treated area. insulin will be allowed to penetrate into the microinjuries created by the microneedling for about 30 mins . Patient will be asked for consideration of aftercare instructions ,including avoiding sun exposure , harsh skincare products and strenuous exercise for few days.
Microneedling with topical insulin
Patients in group B will undergo Microneedling with Topical insulin ( regular).
Interventions
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Microneedling with autologous Platelet Rich Plasma
Patients in group A will undergo Microneedling with autologous PRP
Microneedling with topical insulin
Patients in group B will undergo Microneedling with Topical insulin ( regular).
Eligibility Criteria
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Inclusion Criteria
\-
Exclusion Criteria
18 Years
50 Years
ALL
No
Sponsors
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Khyber Teaching Hospital
OTHER
Responsible Party
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Soaiba Naeem
Doctor
Locations
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Khyber Teaching Hospital
Peshawar, KPK ,Pakistan, Pakistan
Countries
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Central Contacts
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Other Identifiers
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938/DME/KMC
Identifier Type: -
Identifier Source: org_study_id
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