Erbium-YAG Laser Versus Platelet Rich Plasma in the Treatment of Atrophic Acne Scars

NCT ID: NCT03933033

Last Updated: 2019-05-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

75 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-06-01

Study Completion Date

2019-02-28

Brief Summary

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This study aim to assess the efficacy of Er-YAG laser 2940nm and PRP as a single line of treatment in comparison with combined treatment in atrophic post acne scars.

Detailed Description

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Conditions

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Acne Vulgaris Scars

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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Group A

treated with platelet rich plasma

Group Type ACTIVE_COMPARATOR

Platelet Rich Plasma

Intervention Type PROCEDURE

Multiple injections of Platelet Rich Plasma

Group B

treated with Erbium Yag Laser

Group Type ACTIVE_COMPARATOR

Fractional Erbium Yağ Laser

Intervention Type DEVICE

Multiple sessions of Fractional Erbium Yağ Laser

Group C

treated with both line of treatments

Group Type ACTIVE_COMPARATOR

Fractional Erbium Yağ Laser

Intervention Type DEVICE

Multiple sessions of Fractional Erbium Yağ Laser

Platelet Rich Plasma

Intervention Type PROCEDURE

Multiple injections of Platelet Rich Plasma

Interventions

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Fractional Erbium Yağ Laser

Multiple sessions of Fractional Erbium Yağ Laser

Intervention Type DEVICE

Platelet Rich Plasma

Multiple injections of Platelet Rich Plasma

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* patients with atrophic post acne scars classified on the basis of Goodman and Baron's Qualitative classification, no active acne lesions and patients with atrophic scars only

Exclusion Criteria

* patients with positive history of keloidal tendency, positive history of bleeding tendency, platelet disorder, patients with any acute infection on face like, herpes, folliculitis, patients with HIV, HBsAg, patients with a history of autoimmune diseases or patients on immunosuppressive drugs.
Minimum Eligible Age

18 Years

Maximum Eligible Age

38 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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South Valley University

OTHER

Sponsor Role collaborator

Aswan University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Moustafa A. El Taieb

Ass. Prof. of Dermatology, Venereology and Andrology

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Aswan University Hospital

Aswān, , Egypt

Site Status

Countries

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Egypt

References

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El-Taieb MA, Ibrahim HM, Hegazy EM, Ibrahim AK, Gamal AM, Nada EA. Fractional Erbium-YAG Laser and Platelet-Rich Plasma as Single or Combined Treatment for Atrophic Acne Scars: A Randomized Clinical Trial. Dermatol Ther (Heidelb). 2019 Dec;9(4):707-717. doi: 10.1007/s13555-019-00318-1. Epub 2019 Aug 16.

Reference Type DERIVED
PMID: 31420849 (View on PubMed)

Other Identifiers

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Erbium Yag

Identifier Type: -

Identifier Source: org_study_id

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