2940nm Er:YAG Laser Versus Benzoyl Peroxide Gel for the Treatment of Inflammatory Acne

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

25 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-10-31

Study Completion Date

2012-04-30

Brief Summary

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Acne is one of the most common conditions that patients seek for help in dermatological clinic. Nowadays, conventional treatment including topical agents(retinoids, antibiotics ,antiseptics and keratolytic agents) and systemic agents( antibiotics and retinoids) give a satisfying result but not to every patient. Some patients are not well respond to conventional therapy while some patients are unable to tolerate side effects of the treatments. Therefore, interventions to reduce acne are vigorously experimented . Lights and lasers including intense pulsed light, pulsed dye laser with or without photosensitizer and infrared lasers have been found to be useful in treating active inflammatory acne. Although,pain ,downtime and poor response of comedonal acne are limitations of those lights and lasers therapy. 2940 nm Erbium:YAG laser which has both resurfacing and photothermal effects is our laser of interest to seek for its efficacy in the treatment of inflammatory acne.

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Detailed Description

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Conditions

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Acne Vulgaris

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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Er:YAG laser

Group Type EXPERIMENTAL

2940 nm Er:YAG laser (DualisXS M002-2A, Fotona®, Fotona d.d, Ljubljana, Slovenia)

Intervention Type DEVICE

2 passes of 2940nm Er:YAG laser

BP gel

Group Type ACTIVE_COMPARATOR

Benzoyl Peroxide gel

Intervention Type DRUG

2.5% benzoyl peroxide gel apply twice daily on inflammatory acne on the control side of face

Interventions

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2940 nm Er:YAG laser (DualisXS M002-2A, Fotona®, Fotona d.d, Ljubljana, Slovenia)

2 passes of 2940nm Er:YAG laser

Intervention Type DEVICE

Benzoyl Peroxide gel

2.5% benzoyl peroxide gel apply twice daily on inflammatory acne on the control side of face

Intervention Type DRUG

Other Intervention Names

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DualisXS M002-2A, Fotona®, Fotona d.d, Ljubljana, Slovenia 2.5% benzoyl peroxide gel

Eligibility Criteria

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Inclusion Criteria

* Age 18 year-old to 45 year-old
* Mild to moderate severity of acne vulgaris with at least 5 active inflammatory acne lesions on each side of the face and less than 25% difference in lesion count between each side of face
* Fitzpatrick skin phototype I-IV

Exclusion Criteria

* History or clinical presentation of hypertrophic scar or keloid
* Photoaggravated skin diseases i.e. systemic lupus erythematosus, polymorphous light eruption, solar urticaria
* Oral isotretinoin taken within the last 6 months prior to enrollment
* Topical retinoid within 4 weeks prior to enrollment
* Systemic acne therapies (oral antibiotics) within 4 week prior to enrollment

Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No