Efficacy and Safety of IDP-120 Gel in the Treatment of Acne Vulgaris

NCT ID: NCT03003247

Last Updated: 2017-12-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

364 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-11-30

Study Completion Date

2016-09-30

Brief Summary

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Efficacy and Safety of IDP-120 Gel in the Treatment of Acne Vulgaris

Detailed Description

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A Phase 2, Multi-Center, Randomized, Double-Blind, Vehicle- Controlled, Parallel-Group, Clinical Study Comparing the Efficacy and Safety of IDP-120 Gel in the Treatment of Acne Vulgaris

Conditions

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Acne Vulgaris

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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IDP-120 Gel

IDP-120 Gel is a combination treatment

Group Type EXPERIMENTAL

IDP-120 Gel

Intervention Type DRUG

IDP-120 Gel is a combination product

IDP-120 Component A Gel

IDP-120 Monad Gel of Component A

Group Type ACTIVE_COMPARATOR

IDP 120 Component A Gel

Intervention Type DRUG

Monad of Component A

IDP-120 Component B Gel

IDP-120 Monad Gel of Component B

Group Type ACTIVE_COMPARATOR

IDP 120 Component B Gel

Intervention Type DRUG

Monad of Component B

IDP-120 Vehicle Gel

IDP-120 Vehicle Gel

Group Type PLACEBO_COMPARATOR

IDP 120 Vehicle Gel

Intervention Type DRUG

Vehicle

Interventions

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IDP-120 Gel

IDP-120 Gel is a combination product

Intervention Type DRUG

IDP 120 Component A Gel

Monad of Component A

Intervention Type DRUG

IDP 120 Component B Gel

Monad of Component B

Intervention Type DRUG

IDP 120 Vehicle Gel

Vehicle

Intervention Type DRUG

Other Intervention Names

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Component A + B Component A Component B Vehicle

Eligibility Criteria

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Inclusion Criteria

* Male or female at least 9 years of age and older;
* Written and verbal informed consent must be obtained. Subjects less than age of consent must sign an assent for the study and a parent or a legal guardian must sign the informed consent (if subject reaches age of consent during the study they should be re-consented at the next study visit)
* Pre-menses females and women of childbearing potential must have a negative urine pregnancy test at screening visit, and a negative urine pregnancy test at baseline visit.
* Subjects must be willing to comply with study instructions and return to the clinic for required visits. Subjects under the age of consent must be accompanied by the parent or legal guardian at the time of assent/consent signing.
* If a cleanser, moisturizer or sunscreen is needed during the study, Subjects must be willing to use only allowed cleansers, moisturizers, sunscreens, or moisturizer/sunscreen combination products. If the subject wears makeup they must agree to use non-comedogenic makeup.

Exclusion Criteria

* Use of an investigational drug or device within 30 days of enrollment or participation in a research study concurrent with this study.
* Any dermatological conditions on the face that could interfere with clinical evaluations such as acne conglobata, acne fulminans, secondary acne, perioral dermatitis, clinically significant rosacea, gramnegative folliculitis.
* Any underlying disease(s) or some other dermatological condition of the face that requires the use of interfering topical or systemic therapy or makes evaluations and lesion count inconclusive.
* Subjects with a facial beard or mustache that could interfere with the study assessments.
Minimum Eligible Age

9 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Bausch Health Americas, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Anya Loncaric

Role: STUDY_DIRECTOR

Valeant Pharmaceuticals

Locations

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Valeant Site 15

Encino, California, United States

Site Status

Valeant Site 13

Lake Mary, Florida, United States

Site Status

Valeant Site 16

Miami, Florida, United States

Site Status

Valeant Site 14

Tampa, Florida, United States

Site Status

Valeant Site 02

West Palm Beach, Florida, United States

Site Status

Valeant Site 21

Atlanta, Georgia, United States

Site Status

Valeant Site 23

South Bend, Indiana, United States

Site Status

Valeant Site 09

Detroit, Michigan, United States

Site Status

Valeant Site 24

Minneapolis, Minnesota, United States

Site Status

Valeant Site 11

Saint Joseph, Missouri, United States

Site Status

Valreant Site 05

New York, New York, United States

Site Status

Valeant Site 06

New York, New York, United States

Site Status

Valeant Site 01

Chapel Hill, North Carolina, United States

Site Status

Valeant Site 17

High Point, North Carolina, United States

Site Status

Valeant Site 22

Columbus, Ohio, United States

Site Status

Valeant Site 04

Knoxville, Tennessee, United States

Site Status

Valeant Site 07

Austin, Texas, United States

Site Status

Valeant Site 12

Austin, Texas, United States

Site Status

Valeant Site 18

San Antonio, Texas, United States

Site Status

Valeant Site 25

Spokane, Washington, United States

Site Status

Valeant Site 10

Winnepeg, Manitoba, Canada

Site Status

Valeant Site 03

Markham, Ontario, Canada

Site Status

Valeant Site 08

Waterloo, Ontario, Canada

Site Status

Valeant Site 20

Windsor, Ontario, Canada

Site Status

Countries

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United States Canada

Other Identifiers

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V01-120A-201

Identifier Type: -

Identifier Source: org_study_id