Efficacy of Handheld Acne Heat Device

NCT ID: NCT01613924

Last Updated: 2015-12-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

PHASE4

Study Classification

INTERVENTIONAL

Study Start Date

2013-07-31

Study Completion Date

2014-06-30

Brief Summary

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The aim of our study is to determine the time to resolution of individual acne lesions using a popular handheld heat based device in comparison to no treatment and to standard topical therapy with benzoyl peroxide in order to determine its effectiveness in the spot treatment of acne vulgaris. Patient satisfaction and potential side effects will be examined as well.

Detailed Description

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Conditions

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Acne Vulgaris

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Heat based treatment/no treatment

Split face treatment with handheld acne heat based device and no treatment

Group Type PLACEBO_COMPARATOR

Split face: handheld acne heat based device (Zeno Hot Spot) and no treatment

Intervention Type DEVICE

Subjects will apply the actual device to every inflammatory acne facial lesion on one half of the face and no treatment to every inflammatory acne lesion on the other half of the face at 6 hour intervals for a total of 3 treatments. Follow up will occur daily over a 5 day period.

Heat based treatment/benzoyl peroxide

Split face treatment with handheld acne heat based device and benzoyl peroxide 4%

Group Type ACTIVE_COMPARATOR

Split face: handheld acne heat based device, Zeno Hot Spot, and topical benzoyl peroxide 4%

Intervention Type DEVICE

Subjects will apply the actual device to every inflammatory acne facial lesion on one half of the face at 6 hour intervals for a total of 3 treatments. Subjects will apply benzoyl peroxide to the other half of the face daily for 5 days.

Interventions

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Split face: handheld acne heat based device (Zeno Hot Spot) and no treatment

Subjects will apply the actual device to every inflammatory acne facial lesion on one half of the face and no treatment to every inflammatory acne lesion on the other half of the face at 6 hour intervals for a total of 3 treatments. Follow up will occur daily over a 5 day period.

Intervention Type DEVICE

Split face: handheld acne heat based device, Zeno Hot Spot, and topical benzoyl peroxide 4%

Subjects will apply the actual device to every inflammatory acne facial lesion on one half of the face at 6 hour intervals for a total of 3 treatments. Subjects will apply benzoyl peroxide to the other half of the face daily for 5 days.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Are 12- 64 years old
* Have an Investigator's Global Assessment of greater than or equal to 2
* Have 8-16 inflammatory acne facial lesions (papules and pustules)

Exclusion Criteria

* Have any severe facial acne at baseline, including large acne lesions and cysts (nodulocystic acne)
* Have used any topical anti-acne medications, systemic antibiotics, and/or systemic corticosteroids 4 weeks before the study start
* Have used oral acne medications, such as Accutane (systemic retinoid), 6 months before the study start
* Have had a facial procedure 2 weeks before the study start
* Are nursing or pregnant
* Are using any oral contraceptives that have a specific anti-androgenic action or if you have started using a new oral contraceptive 12 weeks before the study start
* Are using any medications known to exacerbate acne
* Have a known hypersensitivity or allergy to benzoyl peroxide or any of the vehicle constituents
* Have a beard or facial hair that could interfere with study evaluations
Minimum Eligible Age

12 Years

Maximum Eligible Age

64 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of British Columbia

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Shannon Humphrey, MD, FRCPC

Role: PRINCIPAL_INVESTIGATOR

UBC Department of Dermatology and Skin Science

Locations

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Skin Care Centre

Vancouver, British Columbia, Canada

Site Status

Countries

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Canada

Other Identifiers

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H12-00792

Identifier Type: -

Identifier Source: org_study_id