Glutamate Modulation of tDCS Over Premotor Cortex Combined With Peripheral Nerve Stimulation Promoted Observation-execution-related Cortical Excitability and Motor Learning

NCT ID: NCT06694909

Last Updated: 2024-11-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

128 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-10-17

Study Completion Date

2018-10-14

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study aimed to investigate whether concurrent tDCS over the PMC and PNS during action observation enhance observation-execution-related motor cortex excitability and improve motor performance, and to explore the underlying mechanism

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Brain Stimulation Peripheral Nerve Stimulation Motor Observation Cortical Excitability

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Participants

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

tDCS + PNS with action observation

Group Type EXPERIMENTAL

tDCS + PNS without action observation

Intervention Type DEVICE

tDCS: transcranial direct current stimulation; PNS: peripheral nerve stimulation

sham tDCS + sham PNS with action observation

Group Type EXPERIMENTAL

sham tDCS + sham PNS with action observation

Intervention Type DEVICE

tDCS: transcranial direct current stimulation; PNS: peripheral nerve stimulation

tDCS + PNS without action observation

Group Type EXPERIMENTAL

sham tDCS + PNS with action observation

Intervention Type DEVICE

tDCS: transcranial direct current stimulation; PNS: peripheral nerve stimulation

sham tDCS + PNS with action observation

Group Type ACTIVE_COMPARATOR

tDCS + PNS with action observation

Intervention Type DEVICE

tDCS: transcranial direct current stimulation; PNS: peripheral nerve stimulation

tDCS + sham PNS with action observation

Group Type ACTIVE_COMPARATOR

tDCS + sham PNS with action observation

Intervention Type DEVICE

tDCS: transcranial direct current stimulation; PNS: peripheral nerve stimulation

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

tDCS + PNS with action observation

tDCS: transcranial direct current stimulation; PNS: peripheral nerve stimulation

Intervention Type DEVICE

sham tDCS + sham PNS with action observation

tDCS: transcranial direct current stimulation; PNS: peripheral nerve stimulation

Intervention Type DEVICE

tDCS + PNS without action observation

tDCS: transcranial direct current stimulation; PNS: peripheral nerve stimulation

Intervention Type DEVICE

sham tDCS + PNS with action observation

tDCS: transcranial direct current stimulation; PNS: peripheral nerve stimulation

Intervention Type DEVICE

tDCS + sham PNS with action observation

tDCS: transcranial direct current stimulation; PNS: peripheral nerve stimulation

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* normal or corrected-to-normal vision
* right-handed

Exclusion Criteria

* pregnancy
* a history of epilepsy
* implanted medical devices
* history or presence of neurological, psychiatric or musculoskeletal disorders, other medical conditions, and left-handedness
Minimum Eligible Age

18 Years

Maximum Eligible Age

33 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Beijing Sport University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Beijing Sport University

Beijing, Haidian, China

Site Status

Countries

Review the countries where the study has at least one active or historical site.

China

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

GMOTOPCCWPNSPOERCEAML

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.