Avoidant and Restrictive Food Intake Disorders (ARFID) in Adolescence: Early Oral Development, Psychopathological Profile and Sensory Integration

NCT ID: NCT06665802

Last Updated: 2024-10-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

90 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-11-30

Study Completion Date

2025-11-30

Brief Summary

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The purpose of this study is to assess if adolescents affected with Avoidant and Restrictive Food Intake Disorders (ARFID) had more frequent precocious pediatric feeding disorders before 4 years old compared to healthy adolescents.

Detailed Description

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This research focuses on retrospective analysis of early pediatric feeding disorders seen for ARFID in adolescence in two departments of the DMU MEFADO.

This assessment will be implemented during a hospital visit by a questionnaire completed by the patient's parents covering the first years of the child's life in medical, behavioural and dietary terms. This questionnaire was created for this study and, therefore, is not validated for general population. The parents will also complete the Montreal Children Feeding scale based on their memories.

The Montreal Children Feeding scale is a validated parental self-questionnaire, allowing the screening of feeding and eating disorders in children under 6 years old. Since the study specific questionnaire is not validated, 60 non-ARFID controls will be included in the study for questionnaires completion. The research also focuses on the psychopathological profile of these adolescents with ARFID regarding their degree of anxiety, their degree of depression, their possible autistic traits and their sensory sensitivity. These aspects will be studied by validated self- and hetero-questionnaires standardized for these fields. The emotional expression of the parents will be assessed during a brief qualitative interview type "Five-Minute Speech Sample".

Conditions

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Avoidant and Restrictive Food Intake Disorders

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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ARFID adolescents

Children between 12 and 17 years old diagnosed with ARFID less than 2 years prior

Questionnaire

Intervention Type BEHAVIORAL

Questionnaire completion

Non ARFID adolescents

Children between 12 and 17 years old with no organic or psychological illness diagnosed

Questionnaire

Intervention Type BEHAVIORAL

Questionnaire completion

Interventions

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Questionnaire

Questionnaire completion

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

For all patients:

* Adolescent aged 12 to 18 (minors = 17 years 11 months)
* No opposition from parents and adolescent

For ARFID patients:

* Consulting at MDA or Necker for an ARFID diagnosed using DSM V criteria
* Whose first consultation for this disorder was less than 2 years ago

For non-ARFID patients:

* Consulting or hospitalized in orthopaedic surgery at Necker Hospital or Robert Debré Hospital for an acute traumatic reason
* Not diagnosed with a chronic illness

Exclusion Criteria

For all patients:

\- Parents and adolescents who do not speak French well enough to understand the questions on the scales and questionnaires

For ARFID patients:

\- Diagnosis of autism spectrum disorder already made at the time of the consultation

For non-ARFID patients:

\- Presence of a chronic organic or psychological illness, to limit the risk of including non ARFID patients at high risk of eating disorders
Minimum Eligible Age

12 Years

Maximum Eligible Age

17 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assistance Publique - Hôpitaux de Paris

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Hôpital Cochin

Paris, , France

Site Status

Hôpital Necker - Enfants malades

Paris, , France

Site Status

Hôpital Robert Debré

Paris, , France

Site Status

Countries

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France

Central Contacts

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Corinne BLANCHET, MD

Role: CONTACT

01 58 41 24 26 ext. +33

Gael PLASTOW

Role: CONTACT

01 44 38 18 57 ext. +33

Facility Contacts

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Corinne BLANCHET, MD

Role: primary

Véronique ABADIE, MD, PhD

Role: primary

Stéphanie PANNIER, MD, PhD

Role: backup

Anne-Laure SIMON, MD

Role: primary

References

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Abadie V. [Diagnostic approach in oral disorder in young children]. Arch Pediatr. 2004 Jun;11(6):603-5. doi: 10.1016/j.arcped.2004.03.040. No abstract available. French.

Reference Type BACKGROUND
PMID: 15158850 (View on PubMed)

Rein Z, Perdereau F, Curt F, Jeammet P, Fermanian J, Godart N. Expressed emotion and anorexia nervosa: the validation of the Five-Minute Speech Sample in reference to the Camberwell Family Interview. Int J Eat Disord. 2006 Apr;39(3):217-23. doi: 10.1002/eat.20245.

Reference Type BACKGROUND
PMID: 16511834 (View on PubMed)

Goday PS, Huh SY, Silverman A, Lukens CT, Dodrill P, Cohen SS, Delaney AL, Feuling MB, Noel RJ, Gisel E, Kenzer A, Kessler DB, Kraus de Camargo O, Browne J, Phalen JA. Pediatric Feeding Disorder: Consensus Definition and Conceptual Framework. J Pediatr Gastroenterol Nutr. 2019 Jan;68(1):124-129. doi: 10.1097/MPG.0000000000002188.

Reference Type BACKGROUND
PMID: 30358739 (View on PubMed)

Fisher MM, Rosen DS, Ornstein RM, Mammel KA, Katzman DK, Rome ES, Callahan ST, Malizio J, Kearney S, Walsh BT. Characteristics of avoidant/restrictive food intake disorder in children and adolescents: a "new disorder" in DSM-5. J Adolesc Health. 2014 Jul;55(1):49-52. doi: 10.1016/j.jadohealth.2013.11.013. Epub 2014 Feb 5.

Reference Type BACKGROUND
PMID: 24506978 (View on PubMed)

Diagnosis and Statistical Manual of Mental Disorders: DSM-5. 5th ed. Washington, DC, USA: American Psychiatric Association (2013).

Reference Type BACKGROUND

Monteleone P, Di Genio M, Monteleone AM, Di Filippo C, Maj M. Investigation of factors associated to crossover from anorexia nervosa restricting type (ANR) and anorexia nervosa binge-purging type (ANBP) to bulimia nervosa and comparison of bulimia nervosa patients with or without previous ANR or ANBP. Compr Psychiatry. 2011 Jan-Feb;52(1):56-62. doi: 10.1016/j.comppsych.2010.05.002. Epub 2010 Jul 1.

Reference Type BACKGROUND
PMID: 21220066 (View on PubMed)

Galmiche M, Dechelotte P, Lambert G, Tavolacci MP. Prevalence of eating disorders over the 2000-2018 period: a systematic literature review. Am J Clin Nutr. 2019 May 1;109(5):1402-1413. doi: 10.1093/ajcn/nqy342.

Reference Type BACKGROUND
PMID: 31051507 (View on PubMed)

Related Links

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http://inforalite.fr

website for parents and professionals about pediatric feeding disorders

https://ffab.fr/

website about eating behaviour of adolescents especially anorexia and bulimia nervosa

Other Identifiers

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2024-A01593-44

Identifier Type: OTHER

Identifier Source: secondary_id

APHP240861

Identifier Type: -

Identifier Source: org_study_id

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