Fear, Gastrointestinal Distress, and Interoception: Physiological and Psychological Mechanisms in Eating Disorders

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

152 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-04-22

Study Completion Date

2025-12-31

Brief Summary

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The proposed study tests fear, gut peptide response, and perceptions of fullness as causes of gastrointestinal distress and eating disorder maintenance.

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Detailed Description

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Conditions

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Feeding and Eating Disorders

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Participants

Study Groups

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High Fat Yogurt - Low Fat Yogurt

Participants will eat yogurt described as 'high fat' at Study Visit 2 and yogurt described as 'low fat' at Study Visit 3.

Group Type OTHER

Test meal description changed

Intervention Type OTHER

Using a within-subjects crossover design, on two separate mornings participants will eat yogurt described as 'high fat' and 'low fat.' In actuality, the meals will not differ.

Low Fat Yogurt - High Fat Yogurt

Participants will eat yogurt described as 'low fat' at Study Visit 2 and yogurt described as 'high fat' at Study Visit 3.

Group Type OTHER

Test meal description changed

Intervention Type OTHER

Using a within-subjects crossover design, on two separate mornings participants will eat yogurt described as 'high fat' and 'low fat.' In actuality, the meals will not differ.

Interventions

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Test meal description changed

Using a within-subjects crossover design, on two separate mornings participants will eat yogurt described as 'high fat' and 'low fat.' In actuality, the meals will not differ.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* female
* DSM-5 eating disorder
* score 16 or higher on the Clinical Impairment Assessment
* experience nausea or stomachache after eating at least "sometimes"
* 18 to 40 years old
* body mass index between 18.5 and 26.5 kg/m2

Exclusion Criteria

* medical conditions affect appetite or weight
* Recent pregnancy or current breastfeeding
* Dairy, strawberry or honey food allergy
* Specific phobia, blood-injection-injury type

Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No