Determinants of Bone Dimensional Changes After Extraction and Alveolar Ridge Preservation
NCT ID: NCT06624982
Last Updated: 2025-11-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
160 participants
OBSERVATIONAL
2025-10-08
2027-10-01
Brief Summary
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Detailed Description
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After providing informed consent and prior to local anesthesia and extraction, the following parameters will be recorded: age, gender, race, medical history, medications, tooth site, reason for extraction and tooth mobility. Gingival width will be recorded prior to local anesthesia and extraction, and at 4 months. Gingival thickness will be recorded after local anesthesia and prior to extraction, and at 4 months. Buccolingual ridge width and ridge height will be recorded immediately before, immediately after extraction, and at 4 months. Immediately after extraction, the following measurements will be recorded: buccal bone thickness, number of roots, root length and width, instruments used for extraction, need for flap elevation, duration of extraction, anesthetic amount, type and approach, and operator experience.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Non-molar sites with immediate post-extraction ridge expansion
Non-molar sites with an increase of buccolingual bone width immediately after tooth extraction compared to pre-extraction.
observational study
Observational study; alveolar ridge preservation
Non-molar sites with no immediate post-extraction ridge width change
Non-molar sites without a change in buccolingual bone width immediately after tooth extraction compared to pre-extraction.
observational study
Observational study; alveolar ridge preservation
Molar sites with immediate post-extraction ridge expansion
Molar sites with an increase of buccolingual bone width immediately after tooth extraction compared to pre-extraction.
observational study
Observational study; alveolar ridge preservation
Molar sites with no immediate post-extraction ridge width change
Molar sites without a change in buccolingual bone width immediately after tooth extraction compared to pre-extraction.
observational study
Observational study; alveolar ridge preservation
Interventions
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observational study
Observational study; alveolar ridge preservation
Eligibility Criteria
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Inclusion Criteria
* Good general health (controlled conditions)
* Controlled periodontal disease
* Scheduled for single tooth extraction with bone graft placement and resorbable membrane
* Tooth to be extracted must have adjacent teeth
* Socket wall integrity
Exclusion Criteria
* Pregnancy
* Active periodontal disease
* Systemic conditions that affect healing
* Lack of socket wall integrity (bone loss ≥50 %) prior to extraction, teeth with severe infection requiring pre-extraction antibiotic treatment to control infection), and contraindications for tooth extraction.
18 Years
75 Years
ALL
Yes
Sponsors
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Marquette University
OTHER
Responsible Party
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Vrisiis Kofina
Director, Advanced Education in Periodontics Program, Assistant Professor of Periodontics
Principal Investigators
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Vrisiis Kofina, DDS, MS
Role: PRINCIPAL_INVESTIGATOR
Marquette University
Locations
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Marquette University School of Dentistry Graduate Periodontics Clinic
Milwaukee, Wisconsin, United States
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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HR-4787
Identifier Type: -
Identifier Source: org_study_id
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