Alveolar Ridge Augmentation Following Tooth Extraction Using Bovine Xenograft With Platelet Rich Fibrin Membrane

NCT ID: NCT05791123

Last Updated: 2023-03-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

14 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-07-15

Study Completion Date

2023-03-05

Brief Summary

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fourteen patients requiring extraction of one posterior tooth with lost buccal bone (\>50%) confirmed preoperatively by Cone-beam computed tomography (CBCT) scans. Extraction sockets were filled with minced PRF clots mixed with the bovine xenograft and covered by PRF membranes to seal the extraction sockets. (CBCT) scans, performed before tooth extraction and after 6 months, were used to assess vertical and horizontal bone changes.

Detailed Description

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Conditions

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Bone Regeneration

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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a bone graft mixed with PRF & covered by PRF membrane in fresh extraction socket

Group Type EXPERIMENTAL

a bone graft mixed with PRF & covered by PRF membrane in fresh extraction socket

Intervention Type PROCEDURE

Extraction sockets were filled with minced PRF clots mixed with the bovine xenograft and covered by PRF membranes to seal the extraction sockets.

Interventions

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a bone graft mixed with PRF & covered by PRF membrane in fresh extraction socket

Extraction sockets were filled with minced PRF clots mixed with the bovine xenograft and covered by PRF membranes to seal the extraction sockets.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients required implant treatment after tooth extraction
* Age group ranged from 20-60 years old.
* Patients could undergo the treatment under local anesthesia.
* Loss of buccal bone (\>50%) confirmed by preoperative cone beam computed tomography (CBCT).
* Presence of other socket walls; mesial, distal and lingual walls.
* Tooth needed to be extracted in upper or lower posterior regions

Exclusion Criteria

* Uncontrolled diabetic diseases.
* Uncontrolled hypertension, or hepatic and renal disorders.
* Any systemic diseases associated with bone metabolism.
Minimum Eligible Age

20 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Future University in Egypt

OTHER

Sponsor Role lead

Responsible Party

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Medhat Sameh Abdelaziz

Assistant Lecturer of Prosthodontics

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Future University in Egypt

Cairo, , Egypt

Site Status

Countries

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Egypt

References

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Elbanna RM, Abdelaziz MS, Alameldeen HE. Augmentation of single tooth extraction socket with deficient buccal walls using bovine xenograft with platelet-rich fibrin membrane. BMC Oral Health. 2023 Nov 17;23(1):874. doi: 10.1186/s12903-023-03554-2.

Reference Type DERIVED
PMID: 37978487 (View on PubMed)

Other Identifiers

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REC-FDBSU/05012023-03/ER

Identifier Type: -

Identifier Source: org_study_id

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