Influence of Platelet-Rich Fibrin on Post-extraction Alveolar Ridge Healing/Preservation as a Stand-alone or Adjunct to Particulate Graft
NCT ID: NCT02707536
Last Updated: 2017-05-04
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
42 participants
INTERVENTIONAL
2014-05-31
2016-05-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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No socket grafting
Extraction with normal socket healing
No interventions assigned to this group
Socket grafting with platelet rich fibrin (PRF) alone
Extraction with socket grafting with platelet rich fibrin (PRF) alone.
Socket grafting with PRF
Extraction with socket grafting using PRF.
Socket grafting with bone grafting alone
Extraction with socket grafting using bone graft (xenograft).
Socket grafting with bone graft
Extraction with socket grafting using bone graft.
Socket grafting with PRF and bone grafting
Extraction with socket grafting using PRF combined with bone graft (xenograft).
Socket grafting with PRF
Extraction with socket grafting using PRF.
Socket grafting with bone graft
Extraction with socket grafting using bone graft.
Interventions
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Socket grafting with PRF
Extraction with socket grafting using PRF.
Socket grafting with bone graft
Extraction with socket grafting using bone graft.
Eligibility Criteria
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Inclusion Criteria
* Hopeless or non-restorable single non-molar tooth per quadrant with adjacent teeth present
* Maximum of two teeth can qualify per patient.
* The buccal plate must be ≥ 1mm in width with a 4-wall configuration.
* Cases requiring minimal sinus grafting (\<3mm)
* Bone grafting limited to the apical portion of the osteotomy site
Exclusion Criteria
* The buccal plate must be ≤ 3mm in width with a 4-wall configuration.
* Patients with uncontrolled or severe systemic disease (Diabetes)
* Patients with medical conditions or taking medication associated with compromised bone healing (Diabetes, Autoimmune Dysfunction, Prolonged Cortisone Therapy, Chemotherapy, or Bisphosphonate Therapy)
* Current Smokers
* Subjects with extensive parafunctional habits (ie; bruxism)
* Subjects who demonstrate inadequate oral hygiene
18 Years
ALL
No
Sponsors
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The University of Texas Health Science Center, Houston
OTHER
Responsible Party
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Sridhar V. K. Eswaran
Assistant Professor
Principal Investigators
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Sridhar Eswaran, BDS, MS, MSD
Role: PRINCIPAL_INVESTIGATOR
The University of Texas Health Science Center, Houston
Locations
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The University of Texas Health Science Center at Houston School of Dentistry
Houston, Texas, United States
Countries
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Other Identifiers
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HSC-DB-14-0190
Identifier Type: -
Identifier Source: org_study_id
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