Interest of the Pleth Variability Index in Neurosurgery
NCT ID: NCT06624891
Last Updated: 2024-10-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
70 participants
INTERVENTIONAL
2023-03-01
2024-08-19
Brief Summary
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The main question it aims to answer is:
• Does the Pleth variability index predict fluid responsiveness in neurosurgery? Researchers will compare the Pleth variability index to dela PP to see if it predicts fluid responsiveness in neurosurgery.
Once participants give their consent, they will be randomly assigned to one of two groups. In one group, fluid responsiveness will be monitored using the Pleth Variability Index, while in the other group, it will be monitored using delta PP.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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pleth variability index (PVI)
Participants will be monitored during the intervention using a Radical-7 Pulse CO-Oximeter to instantly determine the pleth variability index (PVI). If the PVI is more than 14% for at least 5 minutes, 250 ml of gelofusine solution will be given over 10 minutes.
perioperative fluid responsiveness with the Pleth variability index
Perioperative fluid challenge and responsiveness will be based on monitoring the pleth variability index. In fact, volemia will be estimated with the PVI.
delta PP
Participants will be monitored during the intervention using arterial catheter to instantly determine delta PP. If Delta PP is more than 13% for at least 5 minutes, 250 ml of gelofusine solution will be given over 10 minutes.
perioperative fluid responsiveness with delta PP
fluid challenge and responsiveness during intervention will be based on monitoring delta PP.
Interventions
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perioperative fluid responsiveness with the Pleth variability index
Perioperative fluid challenge and responsiveness will be based on monitoring the pleth variability index. In fact, volemia will be estimated with the PVI.
perioperative fluid responsiveness with delta PP
fluid challenge and responsiveness during intervention will be based on monitoring delta PP.
Eligibility Criteria
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Inclusion Criteria
2. Must be aged 18 and over
3. Must be classified as ASA I, ASA II, and ASA III according to the American Society of Anesthesiologists classification
Exclusion Criteria
2. Patients classified ASA IV or higher
3. Cardiac arrhythmia
4. Heart disease with left ventricular ejection fraction less than 45%
5. Obesity with a BMI greater than 40 Kg/m2.
6. Peripheral vascular disease
7. Severe lung disease
8. End-stage renal disease
9. Intraoperative cardiac arrhythmia
10. The occurrence of cardiac arrest
11. The occurrence of hemorrhagic shock
12. Intraoperative use of low tidal volumes or high respiratory rates.
18 Years
ALL
No
Sponsors
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National Institute of Neurology, Tunisia
OTHER
Responsible Party
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Hammami Rabeb
university hospital assistant
Locations
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National Institute of Neurologie Mongi Ben-Hamida
Tunis, , Tunisia
Countries
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Other Identifiers
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PVI IN NEUROSURGERY
Identifier Type: -
Identifier Source: org_study_id
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