Correlation Between ΔPP/HR and ΔSV During Fluid Challenge.

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-06-30

Study Completion Date

2015-11-30

Brief Summary

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In high perioperative risk patients, guidelines suggest intraoperative haemodynamic optimization by measurement of stroke volume (SV) to guide fluid resucitation.This strategy requires an invasive monitoring and learning. Some studies tried to find SV surrogates based on haemodynamic usual parameters. In an experimental hemorrhagic shock, SV was correlated to the pulse pressure (PP) / heart rate (HR) ratio.

The investigators hypothesized that SV variations (ΔSV) would be correlated to the PP/HR ratio variations (ΔPP / HR) during fluid challenge, and ΔPP / HR would be able to detect a ΔSV greater than 10%.

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Detailed Description

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Conditions

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Hypovolemia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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fluid challenge of saline

250 ml of saline

Intervention Type DRUG

Other Intervention Names

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ΔPP/HR and ΔSV

Eligibility Criteria

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Inclusion Criteria

* a suspected hypovolemia, based on clinical or paraclinical parameters.
* a fluid challenge decision at the discretion of the anaesthesiologist physician in charge of the patient.