Feasibility of Deep Inspiratory Internal Jugular Vein Variability in Guiding Preoperative Fluid Replacement

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-08-01

Study Completion Date

2025-06-01

Brief Summary

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Compare the incidence of hypotension during the propofol-induced period between the internal jugular vein variability-guided fluid infusion group and the conventional fluid infusion group through a fluid infusion experiment before anesthesia induction, so as to evaluate the feasibility of using the internal jugular vein variability under deep inspiration to guide preoperative fluid infusion.

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Detailed Description

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Ultrasound records at least one quiet breathing cycle and one deep inhalation cycle to calculate IJVV Propofol was infused target-controlled at 4 μg/ml, and changes in arterial blood pressure within 3 minutes of propofol induction were observed.

Plan to conduct a prospective randomized controlled study to compare the incidence of hypotension during the propofol-induced period between the internal jugular vein variability-guided fluid infusion group and the conventional fluid infusion group through a fluid infusion experiment before anesthesia induction.

Conditions

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Hemodynamic

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

single

Study Groups

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Guiding rehydration group

According to the 421 fluid replacement principle, preoperative fluid replacement is performed

Group Type EXPERIMENTAL

Guiding rehydration

Intervention Type BEHAVIORAL

Preoperative fluid rehydration was performed according to 421 fluid rehydration principles

Conventional rehydration group

rehydrated within 15 minutes according to 0.2ml/kg/min.

Group Type ACTIVE_COMPARATOR

Guiding rehydration

Intervention Type BEHAVIORAL

Preoperative fluid rehydration was performed according to 421 fluid rehydration principles

Interventions

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Guiding rehydration

Preoperative fluid rehydration was performed according to 421 fluid rehydration principles

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* age over 60 years； American Society of Anesthesiology (ASA) status Ⅱ-Ⅲ； Surgery with radial artery puncture； Propofol induction；

Exclusion Criteria

* BMI≥30kg/m2； People with short necks； Previous hypotension (systolic blood pressure \<90mmHg or mean arterial pressure\<65mmHg)； Previous poorly controlled hypertension； Cardiac insufficiency , EF value\<50%； Upper limb deep vein thrombosis； History of radiotherapy or neck surgery； Inability to maintain a supine position for necessary measurements； Mechanical ventilation status or inability to take deep breaths patients； gastrointestinal surgery； Patients allergic to propofol； Restricted fluid intake；

Minimum Eligible Age

60 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No