Prediction of Hypotension During Induction of General Anesthesia

NCT ID: NCT06078228

Last Updated: 2024-08-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

70 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-09-24

Study Completion Date

2024-08-17

Brief Summary

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Post induction hypotension is closely related to postoperative complications. Patients are at high risk of hypotension due to preexisting hypovolemia and the vasodilatory effects of induction agents. Ultrasonographic measurement of the Carotid artery corrected flow time and internal jugular vein collapsibility index may predict post induction hypotension.

Detailed Description

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* Type of Study: Observational Prospective Cohort Design.
* Study Setting and ethical consideration: The approval of the Scientific Research Ethics Committee of the Faculty of Medicine, Ain Shams University will be obtained before starting work on the study. This study will be conducted in operating theatres of Ain Shams University Hospitals. Informed written consents to participate will be obtained from the patients.
* Study Period: One year (October 2023-October 2024)
* Study Population: Adult patient undergoing elective surgeries.

Conditions

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Anesthesia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Propofol - Fentanyl- Atracurium

investigate the reliability of preanesthetic ultrasound measurements of the carotid artery FTc and the internal jugular vein collapsibility index in predicting hypotension during the induction of general anesthesia.

Intervention Type DRUG

Other Intervention Names

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Atropine

Eligibility Criteria

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Inclusion Criteria

* 1- Patients of American Society of Anesthesiologists (ASA) physical status I to II of both genders.

2- Aged 18-65 years. 3- Elective surgeries under general anesthesia. 4- BMI less than 40.

Exclusion Criteria

* Patients with

1. Renal diseases.
2. Hepatic diseases.
3. ASA scores of 3-4.
4. The presence of a left ventricular ejection fraction less than 50%.
5. Age under 18 years old.
6. Patient refusal.
7. Coronary heart disease.
8. Cardiac disease including cardiomyopathy and mild to severe valve disease.
9. Pulmonary hypertension.
10. Peripheral arterial disease.
11. Preoperative cervical vascular ultrasound abnormalities including plaque, stenosis and anatomical variation.
12. Any previous neck surgery or trauma.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Ain Shams University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Marina George, MD candidate

Role: PRINCIPAL_INVESTIGATOR

Ain Shams University

Locations

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Ain Shams University

Cairo, Abbassia, Egypt

Site Status

Countries

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Egypt

Provided Documents

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Document Type: Study Protocol

View Document

Document Type: Informed Consent Form

View Document

Other Identifiers

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FMASU MD205/2023

Identifier Type: -

Identifier Source: org_study_id

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