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Carotis cFT In Prediction Of Hypotension

NCT ID: NCT05896514

Last Updated: 2023-12-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

138 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-06-03

Study Completion Date

2023-12-07

Brief Summary

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The aim of our study is to determine the predictive value of pre-anesthesia FTc for hypotension that may develop after general anesthesia induction in patients over 65 years of age and to investigate the correlation between pre-anesthesia FTc and the magnitude of the maximum decrease in systolic blood pressure from the pre-anaesthetic value.

Detailed Description

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The FTc value of the patients to be included in the study will be measured by ultrasonography 10 minutes before the induction of anesthesia.After the measurement, the patients will be monitored with 3-lead electrocardiography, pulse oximetry and noninvasive blood pressure in the operating room. Before induction of general anesthesia, systolic blood pressure (SBP), diastolic blood pressure (DBP), mean blood pressure (MAP), oxygen saturation and heart rate will measured for 3 minutes at 1-minute intervals. Induction of anesthesia with 1-2 mg/kg propofol, muscle relaxation will be achieved with 0.6 mg/kg intravenous rocuronium. During mask ventilation, 1-2% concentration of sevoflurane and 50-50% oxygen-nitrous oxide will be used. After the anesthesia induction, SBP, DBP, MAP, oxygen saturation and heart rate will be measured for 3 minutes at 1-minute intervals.

Hypotension; defined as a 30% reduction in SBP or a 20% reduction in MAP, or an absolute SBP below 90 mm Hg and MAP below 65 mm Hg within 3 minutes of induction of general anesthesia.Intravenous (iv) noradrenaline and/or iv crystalloid will be used in the treatment of hypotension.

Conditions

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Flow Time Carotid Doppler Ultrasound Hypotension Anesthesia Elderly

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Interventions

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ultrasound-guided carotid artery flow time measurement

Ultrasound-guided corrected carotid artery flow time will be measured before anestesia induction.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* \>65 years old
* undergoing elective surgery under general anesthesia

Exclusion Criteria

* Mean arterial pressure \< 70 mmHg
* Systolic blood pressure \> 180 mmHg
* Diastolic blood pressure \> 110 mmHg
* \< 65 years old
* Carotid artery stenosis \> 50%
* ASA \> 3
* Left ventricle ejection fraction \< 40%
* Severe peripheral vascular disease
* Implanted pacemacer
* Autonomic nervous system disorders
* Heart valve disease
* Chronic kidney disease
* Emergency surgery
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Cukurova University

OTHER

Sponsor Role lead

Responsible Party

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mediha turktan

associate professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Cukurova University

Adana, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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Carotid cFT

Identifier Type: -

Identifier Source: org_study_id