A Correlation Study of Internal Jugular Vein Variability Under Deep Inhalation and Propofol-induced Hypotension

NCT ID: NCT06112769

Last Updated: 2025-03-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

64 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-10-29

Study Completion Date

2024-01-31

Brief Summary

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The correlation between internal jugular vein variability during deep inhalation and the decrease in blood pressure during propofol induction.

Detailed Description

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1. Ultrasound records at least one quiet breathing cycle and one deep inhalation cycle to calculate IJVV
2. Propofol was infused target-controlled at 4 μg/ml, and changes in arterial blood pressure within 3 minutes of propofol induction were observed.
3. Aim to conduct a prospective observational study to evaluate the correlation between internal jugular vein variability during deep inhalation and the decrease in blood pressure during propofol induction.

Conditions

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Hemodynamic

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* age over 60 years
* American Society of Anesthesiology (ASA) status Ⅱ-Ⅲ
* Surgery with radial artery puncture
* Propofol induction

Exclusion Criteria

* BMI≥30kg/m2
* People with short necks;
* Previous hypotension (systolic blood pressure \<90mmHg or mean arterial pressure \<65mmHg)
* Previous poorly controlled hypertension
* Cardiac insufficiency , EF value\<50%
* Upper limb deep vein thrombosis
* History of radiotherapy or neck surgery
* Inability to maintain a supine position for necessary measurements
* Mechanical ventilation status or inability to take deep breaths patients
* gastrointestinal surgery
* patients allergic to propofol.
Minimum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Affiliated Hospital of Jiaxing University

OTHER

Sponsor Role lead

Responsible Party

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Qing-he Zhou

Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Qinghe Zhou

Role: PRINCIPAL_INVESTIGATOR

Affiliated Hospital of Jiaxing University

Locations

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Affiliated Hospital of Jiaxing University

Jiaxing, Zhejiang, China

Site Status

Countries

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China

References

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Wei XL, Xi YZ, Xie L, Li ZP, Tang HL, Zhou QH. Effects of liquid resuscitation guided by internal jugular vein variability during deep inhalation on preventing propofol-induced hypotension in elderly patients. BMC Anesthesiol. 2025 Jul 17;25(1):350. doi: 10.1186/s12871-025-03227-3.

Reference Type DERIVED
PMID: 40676549 (View on PubMed)

Other Identifiers

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2023-KY-603

Identifier Type: -

Identifier Source: org_study_id

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