Monitoring Hypertensive Patients's Cerebral Oxygen Saturation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

41 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-05-31

Study Completion Date

2014-11-30

Brief Summary

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The purpose of this study is to determine whether there is a significant decrease in cerebral oxygen saturation in hypertensive patients undergoing major abdominal surgery and their correlation with standard monitoring parameters.

Detailed Description

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Conditions

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Surgical Complications From General Anesthesia Hypertension Cerebral Ischemia Cerebral Anoxia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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hypertension disease

patients have hypertension disease, whether well-controlled or uncontrolled, more than 3 year

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* patients have hypertension more than 3 year,whether well-controlled or uncontrolled,
* scheduled for major abdominal surgery for at least 2 h
* under general anesthesia
* American Society of Anesthesiologists（ASA）physical status : II \~ III
* Age \> 30

Exclusion Criteria

* pre-existing cerebral pathology for example episodes of cerebral ischemia or stroke;
* ASA physical status \>IV
* hepatic failure
* renal failure
* preoperative Mini-Mental State Examination (MMSE) score less than 24
* a history of cardiovascular surgery or craniotomy
* cardiac failure
* respiratory failure

Minimum Eligible Age

30 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Li Hongyi

Department of Anesthesiology, Tongji Hospital of Tongji Medical College

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Peng Wang, MD PHD

Role: STUDY_DIRECTOR

Vice Director

Locations

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Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, China

Site Status

Countries

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China

References

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Li H, Fu Q, Wu Z, Sun J, Manyande A, Yang H, Wang P. Cerebral oxygen desaturation occurs frequently in patients with hypertension undergoing major abdominal surgery. J Clin Monit Comput. 2018 Apr;32(2):285-293. doi: 10.1007/s10877-017-0024-0. Epub 2017 May 9.

Reference Type DERIVED

PMID: 28488169 (View on PubMed)

Other Identifiers

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75888

Identifier Type: OTHER

Identifier Source: secondary_id

TJH-AD-12888

Identifier Type: -

Identifier Source: org_study_id