Pleth Variability Index as a Predictor for Post-induction Hypotension in Elderly Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

85 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-08-01

Study Completion Date

2025-01-01

Brief Summary

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Hypotension after induction of general anesthesia and before surgical stimulation is a prevalent anesthesia-related side effect. The post-induction hypotension disrupts organ perfusion and may cause organ damage particularly acute kidney injury, cerebrovascular stroke, and myocardial ischemia. Post-induction hypotension occurs with greater frequency and severity in the elderly. This is because of aged-related diminished cardiac reserve and impaired autonomic homeostasis. Pleth variability index (PVI) is a software program that measures the dynamic changes of the PI that occurs during a complete respiratory cycle. Our primary outcome is to determine the predictive ability and the optimal cut-off value of pre-anesthesia PVI for predicting elderly patients who are at risk of developing post-induction hypotension

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Detailed Description

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Conditions

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Post-induction Hypotension

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Pleth variability index for prediction of post-induction hypotension

The use of the baseline Pleth variability index values for prediction of occurrence of post-induction hypotension

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* patients with ASA physical status I or II
* patients will receive general anesthesia

Exclusion Criteria

* Patients with a history of cardiorespiratory disorders
* patients with uncontrolled hypertension or cardiac dysrhythmias
* Patients with renal or hepatic diseases.
* Patients with long-standing diabetes and peripheral vascular diseases.

Minimum Eligible Age

65 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No