Predictor of Postoperative Complications After Lengthy Noncardiac Surgery
NCT ID: NCT04680663
Last Updated: 2025-01-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
235 participants
OBSERVATIONAL
2021-03-15
2024-06-10
Brief Summary
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Hyperlactacidemia can cause disturbance of internal environment, then leading to increased complications and longer ICU stay, even death. For postoperative patients, we must ensure adequate perfusion in order to minimize the length of hyperglycemia and improve patients' outcomes. With regard to lactate, it provides information about prefusion, but not timely enough for its delay on reflecting hypoperfusion. And it's not real-time and non-invasive.
Peripheral perfusion index (PPI) is an indicator reflecting hypoperfusion in critical patients. It is measured using pulse co-oximetry technology which is characterized by being real-time and noninvasive. PPI is defined as "the ratio of pulsatile blood flow to the non-pulsatile blood flow", mirroring the strength of blood flow and quality of perfusion at sensor site, reflecting perfusion state of the body part . In contrast to lactate value, it's real-time and easy to monitor.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Non complications group
where the non-complicated patients is the patients running the normal postoperative course of surgery and without any need for intervention
Peripheral Perfusion index
Peripheral Perfusion index is the ratio between pulsatile blood flow to non pulsatile blood flow or static blood in the peripheral tissue
serum lactate level
Blood lactate (product of metabolism) level is maintained by a cycle of continuous production and metabolism allowing it to be kept within normal values
complications group
any deviation from the normal post-operative course
Peripheral Perfusion index
Peripheral Perfusion index is the ratio between pulsatile blood flow to non pulsatile blood flow or static blood in the peripheral tissue
serum lactate level
Blood lactate (product of metabolism) level is maintained by a cycle of continuous production and metabolism allowing it to be kept within normal values
Interventions
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Peripheral Perfusion index
Peripheral Perfusion index is the ratio between pulsatile blood flow to non pulsatile blood flow or static blood in the peripheral tissue
serum lactate level
Blood lactate (product of metabolism) level is maintained by a cycle of continuous production and metabolism allowing it to be kept within normal values
Eligibility Criteria
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Inclusion Criteria
* Both genders
* surgical time planned to be \> 120 minutes .
* surgical time predicted to exceed the planned time and prolongation of surgical time \> 120 minutes occured will be included in the study .
* ASA physical status of I-II
* Patients scheduled for elective surgery under general anaesthesia .
Exclusion Criteria
* patient with disease affecting blood flow to the hands where probe will be applied .
* patient with hand injuries so probe cannot be applied
* Patient with sever renal and liver disease
* Discharging against medical advice or reported death during ICU stay at first 48 hours after ICU admission .
* Pregnancy or emergency surgery .
* shortening of the planned surgical time to be less than 120 minutes
18 Years
ALL
No
Sponsors
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Cairo University
OTHER
Responsible Party
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Amr Samir Wahdan
Assistant Professor of Anesthesia, Pain management and Surgical ICU
Principal Investigators
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Amr s wahdan, MD
Role: PRINCIPAL_INVESTIGATOR
Cairo university , Cairo, Egypt
Locations
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Cairo university
Cairo, , Egypt
Countries
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Other Identifiers
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MS-390-2020
Identifier Type: -
Identifier Source: org_study_id
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