Relationships Between Exercise and Appetite in Women With Loss of Control Eating

NCT ID: NCT06602973

Last Updated: 2025-05-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

26 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-08-30

Study Completion Date

2026-08-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This pilot study is a first step in looking at the relationship between exercise and appetite in women with loss of control eating.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Eating Disorders Binge-Eating Disorder Bulimia Nervosa

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Rest, Fed Exercise, Fasted Exercise

At Study Visit 2, participants will eat breakfast and rest (abstain from exercise).

At Study Visit 3, participants will eat breakfast and exercise. At Study Visit 4, participants will abstain from breakfast and will engage in exercise.

Group Type EXPERIMENTAL

Rest

Intervention Type BEHAVIORAL

Participants will eat breakfast but abstain from exercise

Fed Exercise

Intervention Type BEHAVIORAL

Participants will eat breakfast and engage in 30 minutes of physical activity at 75% of their personal V02max.

Fasted Exercise

Intervention Type BEHAVIORAL

Participants will engage in 30 minutes of physical activity at their personal 75% V02max after abstaining from breakfast.

Rest, Fasted Exercise, Fed Exercise

At Study Visit 2, participants will eat breakfast and rest (abstain from exercise).

At Study Visit 3, participants will abstain from breakfast and will engage in exercise.

At Study Visit 4, participants will eat breakfast and exercise.

Group Type EXPERIMENTAL

Rest

Intervention Type BEHAVIORAL

Participants will eat breakfast but abstain from exercise

Fed Exercise

Intervention Type BEHAVIORAL

Participants will eat breakfast and engage in 30 minutes of physical activity at 75% of their personal V02max.

Fasted Exercise

Intervention Type BEHAVIORAL

Participants will engage in 30 minutes of physical activity at their personal 75% V02max after abstaining from breakfast.

Fed Exercise, Rest, Fasted Exercise

At Study Visit 2, participants will eat breakfast and exercise. At Study Visit 3, participants will eat breakfast and rest (abstain from exercise).

At Study Visit 4, participants will abstain from breakfast and will engage in exercise.

Group Type EXPERIMENTAL

Rest

Intervention Type BEHAVIORAL

Participants will eat breakfast but abstain from exercise

Fed Exercise

Intervention Type BEHAVIORAL

Participants will eat breakfast and engage in 30 minutes of physical activity at 75% of their personal V02max.

Fasted Exercise

Intervention Type BEHAVIORAL

Participants will engage in 30 minutes of physical activity at their personal 75% V02max after abstaining from breakfast.

Fed Exercise, Fasted Exercise, Rest

At Study Visit 2, participants will eat breakfast and exercise. At Study Visit 3, participants will abstain from breakfast and will engage in exercise.

At Study Visit 4, participants will eat breakfast and rest (abstain from exercise).

Group Type EXPERIMENTAL

Rest

Intervention Type BEHAVIORAL

Participants will eat breakfast but abstain from exercise

Fed Exercise

Intervention Type BEHAVIORAL

Participants will eat breakfast and engage in 30 minutes of physical activity at 75% of their personal V02max.

Fasted Exercise

Intervention Type BEHAVIORAL

Participants will engage in 30 minutes of physical activity at their personal 75% V02max after abstaining from breakfast.

Fasted Exercise, Fed Exercise, Rest

At Study Visit 2, participants will abstain from breakfast and will engage in exercise.

At Study Visit 3, participants will eat breakfast and exercise. At Study Visit 4, participants will eat breakfast and rest (abstain from exercise)

Group Type EXPERIMENTAL

Rest

Intervention Type BEHAVIORAL

Participants will eat breakfast but abstain from exercise

Fed Exercise

Intervention Type BEHAVIORAL

Participants will eat breakfast and engage in 30 minutes of physical activity at 75% of their personal V02max.

Fasted Exercise

Intervention Type BEHAVIORAL

Participants will engage in 30 minutes of physical activity at their personal 75% V02max after abstaining from breakfast.

Fasted Exercise, Rest, Fed Exercise

At Study Visit 2, participants will abstain from breakfast and will engage in exercise.

At Study Visit 3, participants will eat breakfast and rest (abstain from exercise).

At Study Visit 4, participants will eat breakfast and exercise.

Group Type EXPERIMENTAL

Rest

Intervention Type BEHAVIORAL

Participants will eat breakfast but abstain from exercise

Fed Exercise

Intervention Type BEHAVIORAL

Participants will eat breakfast and engage in 30 minutes of physical activity at 75% of their personal V02max.

Fasted Exercise

Intervention Type BEHAVIORAL

Participants will engage in 30 minutes of physical activity at their personal 75% V02max after abstaining from breakfast.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Rest

Participants will eat breakfast but abstain from exercise

Intervention Type BEHAVIORAL

Fed Exercise

Participants will eat breakfast and engage in 30 minutes of physical activity at 75% of their personal V02max.

Intervention Type BEHAVIORAL

Fasted Exercise

Participants will engage in 30 minutes of physical activity at their personal 75% V02max after abstaining from breakfast.

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Engage in loss of control eating at least 12 times in the last three months
* Clinically significant eating disorder-related impairment (CIA \> 15)
* Taking hormonal contraception
* Minimum VO2max of 50th percentile for age and sex assigned at birth
* Be willing to eat study-provided foods
* Likes chocolate (at least 6/10 on 10 point scale)

Exclusion Criteria

* BMI \< 18.5 kgm/2
* Medical conditions that affect appetite or weight (e.g., diabetes mellitus, thyroid disease)
* Recent pregnancy or breastfeeding (prior 6 months)
* Relevant food allergies (e.g., wheat, chocolate)
* Specific phobia, blood-injection-injury type
* Medical condition that precludes safe participation in exercise (e.g., stress fracture)
* Medications that acutely affect appetite (e.g., GLP-1 agonists; psychiatric medications allowed)
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Ohio University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Katherine J. Forney

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Ohio University

Athens, Ohio, United States

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

United States

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

K. Jean Forney, Ph.D.

Role: CONTACT

740-593-1085

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

K. Jean Forney, Ph.D.

Role: primary

740-593-1085

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

IRB_FY24-403

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Self-Control in Bulimia Nervosa
NCT04409457 COMPLETED NA
Treatment of Binge Eating Disorder
NCT00041743 COMPLETED NA