Neural Bases of Multiple Forms of Self-regulatory Control in Bulimia Nervosa

NCT ID: NCT02997475

Last Updated: 2023-01-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

89 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-06-30

Study Completion Date

2022-07-31

Brief Summary

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The purpose of this study is to investigate areas of the brain responsible for self-regulation in adult women who have never had an eating disorder with women who have bulimia nervosa. More specifically, investigators are interested in changes in brain activation (e.g., changes in blood flow and oxygen use) when inhibiting responses and regulating emotions. Data collection will rely on a technology called functional magnetic resonance imaging (fMRI).

Detailed Description

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Conditions

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Bulimia Nervosa

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Women with Bulimia Nervosa

No interventions assigned to this group

Women Healthy Controls

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Female
* Right-handed
* Between the ages of 18 and 35 years

\*For Women with Bulimia Nervosa:
* Binge eating (i.e., eating a large amount of food while experiencing a sense of loss of control)
* Purging via self-induced vomiting (other methods may also be endorsed)

Exclusion Criteria

* Current significant medical illness or condition (e.g., diabetes, thyroid disease)
* Pregnancy, planned pregnancy, or lactation during the study period
* Non-removable metallic objects in the body
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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National Institute of Mental Health (NIMH)

NIH

Sponsor Role collaborator

The Hilda & Preston Davis Foundation

OTHER

Sponsor Role collaborator

University of California, San Diego

OTHER

Sponsor Role lead

Responsible Party

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Walter Kaye

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Laura A. Berner, Ph.D.

Role: STUDY_DIRECTOR

University of California, San Diego

Locations

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UCSD Eating Disorders Center for Treatment and Research

San Diego, California, United States

Site Status

Countries

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United States

Other Identifiers

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F32MH108311

Identifier Type: NIH

Identifier Source: secondary_id

View Link

151514

Identifier Type: -

Identifier Source: org_study_id

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