Brain Activity, Cognitive Function, and Walking Ability in Parkinson's Disease

NCT ID: NCT06588920

Last Updated: 2025-02-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

70 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-10-09

Study Completion Date

2027-08-31

Brief Summary

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The dual-task automated walking performance in people with Parkinson\'s disease (PD) is affected by their gait disturbances and impaired executive functions. Currently, the relationship between brain activity related to inhibitory control, executive functions, and dual-task walking performance in people with PD is not well understood. Therefore, this study aims to investigate the significance of different executive function domains on gait stability in healthy older adults and people with PD; whether brain activation related to inhibitory control is associated with gait stability in healthy older adults and people with PD.

Detailed Description

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Conditions

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Healthy Older Adults Parkinson Disease

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Parkinson disease

People with Parkinson disease

Cognitive function, gait, and electroencephalogram

Intervention Type BEHAVIORAL

Measurement of cognitive function, gait performance, and electroencephalogram

Healthy older adults

Healthy older adults

Cognitive function, gait, and electroencephalogram

Intervention Type BEHAVIORAL

Measurement of cognitive function, gait performance, and electroencephalogram

Interventions

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Cognitive function, gait, and electroencephalogram

Measurement of cognitive function, gait performance, and electroencephalogram

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Diagnoses of idiopathic Parkinson disease
* Stable dopaminergic medicine ≥ 2 weeks
* Able to walk 10 meters without aid
* Mini-Mental Status Examination ≥ 24 points
* No uncorrected visual or auditory disorders
* Education at least junior high school
* No other disease may affect balance

Exclusion Criteria

* Other medical diagnoses of neurological, musculoskeletal, or cardiopulmonary disorders
* History of brain surgery (e.g. deep brain stimulation)
Minimum Eligible Age

40 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Yang Ming Chiao Tung University

OTHER

Sponsor Role lead

Responsible Party

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Yea-Ru Yang

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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National Yang Ming Chiao Tung University

Taipei, , Taiwan

Site Status RECRUITING

National Yang Ming Chiao Tung University

Taipei, , Taiwan

Site Status RECRUITING

Countries

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Taiwan

Central Contacts

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Yea-Ru Yang, PhD

Role: CONTACT

+886228267279

Facility Contacts

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Yea-Ru Yang

Role: primary

Yea-Ru Yang, Professor

Role: primary

886-2-2826-7279

Other Identifiers

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NYCU113006AF1

Identifier Type: -

Identifier Source: org_study_id

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