Gait Control in Parkinson Disease

NCT ID: NCT05908279

Last Updated: 2023-06-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-05-01

Study Completion Date

2027-10-31

Brief Summary

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Previous work has shown that a statistical property of gait characterised by long-range autocorrelation functions is altered in Parkinson disease (PD). On the other hand it has been suggested that the same property is linked to the ability in healthy humans to co-regulate the amplitude and cadence of strides towards maintaining a constant speed. Here the investigators want to better understand why it is altered in PD by measuring the transitions between gait instructed by a metronome, and gait without metronome. The experimental conditions will allow the comparisons between these transitions across PD and healthy groups of volunteers, and assess differences based on statistical and computational modelling. The link with potential freezing episodes will also be studied to assess whether the statistical determinants of gait control in this population can be used as a proxy or predictor of the occurence of freezing episodes.

Detailed Description

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Conditions

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Parkinson Disease

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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PD

Patients with Parkinson's disease

Walking test

Intervention Type OTHER

Walk with and without a metronome

Disease assessement

Intervention Type OTHER

Disease stage assessed by a doctor

Control

Healthy volunteers

Walking test

Intervention Type OTHER

Walk with and without a metronome

Interventions

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Walking test

Walk with and without a metronome

Intervention Type OTHER

Disease assessement

Disease stage assessed by a doctor

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients and volunteers able to walk for 20mins and without other neurological disorders.

Exclusion Criteria

* Patients or volunteers unable to walk for 20mins and with other neurological disorders.
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Université Catholique de Louvain

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Frederic Crevecoeur

Role: STUDY_DIRECTOR

Université Catholique de Louvain

Locations

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Université catholique de Louvain

Louvain-la-Neuve, , Belgium

Site Status RECRUITING

Countries

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Belgium

Central Contacts

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André Mouraux, PhD

Role: CONTACT

+32 2 764 54 47

Frederic Crevecoeur

Role: CONTACT

Facility Contacts

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Andre Mouraux, PhD

Role: primary

+32 2 764 54 47

Other Identifiers

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GAIT-PD

Identifier Type: -

Identifier Source: org_study_id

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