Flexible Reaching Control in Parkinson Disease

NCT ID: NCT05908266

Last Updated: 2023-06-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-05-01

Study Completion Date

2027-10-31

Brief Summary

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Current research and theories have highlighted that the parameters linked to movement planning, e.g. the decision to select a movement goal, and adaptation, e.g. the ability to update control dependent on a novel dynamical context, are update quickly and within an ongoing movement in the general population. In parallel, it has been suggested that the evaluation of movement costs is a function of the basal ganglia, and it is impaired in Parkinson disease (PD). Here the investigators want to test whether these mechanisms also alter the ability of patients to update control during an ongoing action. A positive result would confirm that movement-related costs and dynamical representations depend on the integrity of the basal ganglia, in contrast a negative result would indicate that the deficit in PD is more specifically related to movement initiation, which would invite one to reconsider the cause of bradykinesia in this population.

Detailed Description

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Conditions

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Parkinson Disease

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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PD

Patients with Parkinson disease

Reaching movements

Intervention Type OTHER

Participants will be instructed to perform reaching movements by moving the handle of a robotic arm mounted with a virtual reality display.

Disease Assessment

Intervention Type OTHER

Disease stage assessed by trained professionals

Control

Healthy volunteers

Reaching movements

Intervention Type OTHER

Participants will be instructed to perform reaching movements by moving the handle of a robotic arm mounted with a virtual reality display.

Interventions

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Reaching movements

Participants will be instructed to perform reaching movements by moving the handle of a robotic arm mounted with a virtual reality display.

Intervention Type OTHER

Disease Assessment

Disease stage assessed by trained professionals

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Ability to perform the task (assessed during the experiment)

Exclusion Criteria

* Inability to perform the task (motor) or to understand the task requirements (cognitive)
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Université Catholique de Louvain

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Frédéric Crevecoeur, PhD

Role: STUDY_DIRECTOR

Université Catholique de Louvain

Locations

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Université catholique de Louvain

Louvain-la-Neuve, , Belgium

Site Status RECRUITING

Countries

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Belgium

Central Contacts

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André Mouraux, PhD

Role: CONTACT

+32 2 764 54 47

Frédéric Crevecoeur, PhD

Role: CONTACT

Facility Contacts

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André Mouraux, PhD

Role: primary

+32 2 764 54 47

Other Identifiers

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REACH-PD

Identifier Type: -

Identifier Source: org_study_id

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