Cognitive-motor Training in Parkinson Disease

NCT ID: NCT06588439

Last Updated: 2025-06-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-03-15

Study Completion Date

2027-08-31

Brief Summary

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Literature reviews showed the cognitive-motor training that combines cognitive tasks may enhance cognitive functions more effectively than individual interventions. Stepping-based cognitive-motor training has been shown to improve cognitive functions, balance, and gait performance in older adults. However, there is insufficient research evidence on the impact and correlation of this training mode on the walking ability, executive functions, and brain activity changes in people with PD. Therefore, this study is designed to investigate the effects of stepping-based cognitive-motor training on the walking ability, executive functions, and brain activity in people with PD.

Detailed Description

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Conditions

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Parkinson Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Cognitive-motor training group

Participants receive 16 sessions of cognitive-motor training.

Group Type EXPERIMENTAL

Cognitive-motor training

Intervention Type OTHER

Cognitive-motor training is that cognitive tasks incorporated into motor tasks.

Control group

Participants receive 16 sessions of conventional physiotherapy.

Group Type ACTIVE_COMPARATOR

Conventional physiotherapy

Intervention Type OTHER

Conventional physiotherapy includes stretching, ROM exercise, strengthening exercise, and eye-hand coordination.

Interventions

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Cognitive-motor training

Cognitive-motor training is that cognitive tasks incorporated into motor tasks.

Intervention Type OTHER

Conventional physiotherapy

Conventional physiotherapy includes stretching, ROM exercise, strengthening exercise, and eye-hand coordination.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Diagnoses of idiopathic Parkinson disease
* Stable dopaminergic medicine ≥ 2 weeks
* Able to walk 10 meters without aid
* Mini-Mental Status Examination ≥ 24 points
* No uncorrected visual or auditory disorders
* Education at least junior high school
* No other disease may affect balance

Exclusion Criteria

* Other medical diagnoses of neurological, musculoskeletal, or cardiopulmonary disorders
* History of brain surgery (e.g. deep brain stimulation)
Minimum Eligible Age

40 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Yang Ming Chiao Tung University

OTHER

Sponsor Role lead

Responsible Party

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Yea-Ru Yang

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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National Yang Ming Chiao Tung University

Taipei, , Taiwan

Site Status RECRUITING

Countries

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Taiwan

Central Contacts

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Yea-Ru Yang, PhD

Role: CONTACT

+886228267279

Facility Contacts

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Yea-Ru Yang, PhD

Role: primary

Other Identifiers

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NYCU113006AF2

Identifier Type: -

Identifier Source: org_study_id

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