Effects of Physical Activity on the Brain in Parkinson's Disease (PD)

NCT ID: NCT01741584

Last Updated: 2016-03-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-12-31

Brief Summary

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The aim of the study is to investigate whether exercise improves cognitive and motor functions in Parkinson's disease. To test this hypothesis, the researchers study general brain functions in subjects with PD during a 6-months exercise program.

Detailed Description

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Conditions

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Parkinson's Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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stationary bike exercise

6 months of exercise (60% of anaerobic threshold)

Group Type EXPERIMENTAL

stationary bike exercise

Intervention Type BEHAVIORAL

aerobic

6 months of exercise \<30% anaerobic threshold

Group Type PLACEBO_COMPARATOR

aerobic

Intervention Type BEHAVIORAL

Interventions

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stationary bike exercise

Intervention Type BEHAVIORAL

aerobic

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* UPDRS \<15
* L-DOPA responsive
* \<5 yrs since diagnosis

Exclusion Criteria

* severe other diseases
* MMSE \< 26
* treatment with psychiatric medication
Minimum Eligible Age

35 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Charite University, Berlin, Germany

OTHER

Sponsor Role lead

Responsible Party

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Agnes Flöel

Prof. Dr. med. Agnes Floeel

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Agnes Flöel, MD

Role: PRINCIPAL_INVESTIGATOR

Charite University, Berlin, Germany

Locations

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Department of Neurology, Charité Universitätsmedizin Berlin

Berlin, State of Berlin, Germany

Site Status

Countries

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Germany

Other Identifiers

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PA_memory_01

Identifier Type: -

Identifier Source: org_study_id

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