Research on the Effect and Mechanism of Aerobic Exercise on PD

NCT ID: NCT04651140

Last Updated: 2021-01-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-10-13

Study Completion Date

2021-10-30

Brief Summary

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This trial is expected to recruit patients with primary Parkinson's disease and give them four consecutive weeks of aerobic exercise to observe its effect on Parkinson's disease and explore its mechanism

Detailed Description

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This trial is expected to recruit patients with primary Parkinson's disease who are distributed into tremor group and stiff group and give them the same kind of four consecutive weeks of aerobic exercise to observe its effect on Parkinson's disease and explore its mechanism

Conditions

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Parkinson's Disease Physical Exercise

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Tremor group

Participants in the tremor group have tremor as the main clinical manifestation

Group Type ACTIVE_COMPARATOR

aerobic exercise

Intervention Type BEHAVIORAL

Participants ride an Acon-8650 model exercise bicycle 3 times a week for 1 hour each time for four consecutive weeks

Stiff group

Participants in the tremor group have stiff as the main clinical manifestation

Group Type ACTIVE_COMPARATOR

aerobic exercise

Intervention Type BEHAVIORAL

Participants ride an Acon-8650 model exercise bicycle 3 times a week for 1 hour each time for four consecutive weeks

Interventions

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aerobic exercise

Participants ride an Acon-8650 model exercise bicycle 3 times a week for 1 hour each time for four consecutive weeks

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Participants were diagnosed primary PD according to the 2015 MDS diagnostic criteria
* Participants are between 55 and 65 years old

Exclusion Criteria

* Severe heart
* liver dysfunction
* kidney dysfunction
* severe cognitive dysfunction
* severe anxiety and depression
* history of mental illness
* history of cerebral infarction or ischemic attack in the past three months
* acute myocardial infarction or acute coronary in the past three months
* Parkinson's Pulse syndrome
* medication history (drugs that improve blood circulation in the brain and increase the excitability of the nervous system)
Minimum Eligible Age

55 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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The First Hospital of Jilin University

OTHER

Sponsor Role lead

Responsible Party

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Zhang Ying

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ying Zhang, Doctor

Role: STUDY_DIRECTOR

The First Hospital of Jilin University

Locations

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FirstJilinU

Changchun, , China

Site Status

Countries

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China

Other Identifiers

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Zhang Ying

Identifier Type: -

Identifier Source: org_study_id

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