Cycling and Treadmill With Dual Task for Parkinson's Disease Improvement
NCT ID: NCT06355947
Last Updated: 2024-04-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
50 participants
INTERVENTIONAL
2015-12-07
2018-07-31
Brief Summary
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Studies showed that working memory related dual task walking was a sensitive test for PD. However, the optimal cognitive test needs to be clarified. Studies also showed that the neuromuscular control mechanism of leg movements during cycling were similar to those during walking. Therefore, dual task cycling test is potential to be a safe and sensitive testing model.
Studies showed that exercise could improve cognitive function and induce brain plasticity. Dual task exercise training was shown to be more effective than single task exercise training for older people to prevent fall. Whether the added cognitive task could improve to detriment brain plasticity in PD should be investigated. Transcranial magnetic stimulation can evaluate the motor cortex plasticity on-invasively and can evaluate the exercise induced brain plasticity.
The purpose of this three-year project is to develop PD-sensitive. The purposes of the first year are to translate the dual task walking test to dual task cycling test, and to establish the reliability of the dual task cycling test.
The purposes of the second year are to compare the motor cortex plasticity induced by single task cycling versus dual task cycling and to compare the difference response between PD and healthy control people.
The purpose of the third year is to evaluate the effect of 8 week long term cycling training or treadmill training of individuals with PD on motor cortex plasticity, dual task performance, and ambulation ability.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Stage 1:Healthy people
To establish a baseline and ensure reliability, and to explore the relationship between dual-task gait performance and dual-task cycling
No interventions assigned to this group
No Intervention: Stage 2:PD people
To explore the relationship between dual-task gait and dual-task cycling performances in individuals with Parkinson's Disease (PD)
No interventions assigned to this group
Stage 3:PD cycling training group
Cycling training conducted with cognitive tasks
Cognitive cycling training
Cycling training conducted with cognitive tasks
Stage 3: PD treadmill training group
Treadmill training conducted with cognitive tasks
Cognitive treadmill training
Treadmill training conducted with cognitive tasks
Stage 3:PD Control group
Control group
No interventions assigned to this group
Interventions
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Cognitive cycling training
Cycling training conducted with cognitive tasks
Cognitive treadmill training
Treadmill training conducted with cognitive tasks
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Osteoporosis.
PD subjects:
* Musculoskeletal injuries on legs
* Osteoporosis.
* Any peripheral or central nervous system injury or disease patients.
20 Years
ALL
Yes
Sponsors
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Chang Gung University
OTHER
Responsible Party
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Ya-Ju Chang
Professor
Locations
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Chang Gung University
Taoyuan District, , Taiwan
Countries
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Other Identifiers
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103-7445B
Identifier Type: -
Identifier Source: org_study_id
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