A Comparative Analysis of Intertransverse Nerve Block and Paravertebral Nerve Block in Endoscopic Hepatectomy

NCT ID: NCT06553495

Last Updated: 2024-08-14

Basic Information

• Recruitment Status: ACTIVE_NOT_RECRUITING
• Clinical Phase: NA
• Total Enrollment: 80 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-08-01
• Study Completion Date: 2026-12-31

Brief Summary

This study aims to compare the analgesic effect of intertransverse nerve block and paravertebral nerve block after endoscopic hepatectomy, evaluate its effectiveness and safety, and provide new ideas and clinical basis for postoperative pain management of liver surgery.

Detailed Description

This study was a prospective, double-blind, randomized controlled trial. Patients who were eligible for laparoscopic partial liver resection in our center were included, with intertransverse nerve block as the experimental group and paravertebral nerve block as the control group. Through the analysis of postoperative pain score 30min to 24h, the number of effective analgesic pump compressions within 24h, the amount of analgesic drugs used, complications and other data, To evaluate the efficacy and safety of intertransverse nerve block in patients undergoing laparoscopic partial liver resection.

Conditions

Pain

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: TRIPLE

Study Groups

intertransverse nerve block

To study the analgesic effect of intertransverse nerve block after endoscopic hepatectomy

Group Type: EXPERIMENTAL

Nerve block

Intervention Type: OTHER

Analgesic effect of different nerve blocks

paravertebral nerve block

To study the analgesic effect of paravertebral nerve block after endoscopic hepatectomy

Group Type: PLACEBO_COMPARATOR

Nerve block

Intervention Type: OTHER

Analgesic effect of different nerve blocks

Interventions

Nerve block

Analgesic effect of different nerve blocks

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

1.18-80 years old adult, BMI<27.9kg/m2

2: 2. American Society of Anesthesiologists ASA Grade I-III

3: 3. Patients with laparoscopic partial liver resection such as liver tumors

4: 4. Willing to participate in this study and sign the informed consent form

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Exclusion Criteria

1. 1. The patient or family member refuses to sign the informed consent form

2. 2. Blood coagulation dysfunction, local infection

3. 3. Those who have communication, communication disorders or mental abnormalities

4. 4. Patients with severe heart, pulmonary and renal insufficiency or patients with central system diseases

5. 5. For any reason, it cannot be matched with the study or the researcher believes that it is not appropriate to be included in this experiment.

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• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 80 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Jie Chen

OTHER

Sponsor Role: lead

Responsible Party

Jie Chen

临床教授

Responsibility Role: SPONSOR_INVESTIGATOR

Locations

The Second Affiliated Hospital Of Chongqing Medical University

Chongqing, Chongqing Municipality, China

Countries

China

Other Identifiers

2024-098

Identifier Type: -

Identifier Source: org_study_id