Magnetic Resonance Imaging of Cognitive Deficits in the Brain of Individuals With Spinal Cord Injury

NCT ID: NCT06309888

Last Updated: 2025-11-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

54 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-02-01

Study Completion Date

2024-11-18

Brief Summary

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In the case of spinal cord injury, rehabilitation is particularly focused on motor skills. Non-motor impairments such as thinking difficulties did not receive a lot of attention to date.

In this research project, the investigators want to find out how thinking difficulties become noticeable in the brain with spinal cord injury.

Participation procedure: Participants who take part will be asked to come to an examination once. The duration of the examination is between 2 and 2.5 hours (including around 55 minutes in the magnetic resonance imaging scanner, including preparation and follow-up).

Detailed Description

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Conditions

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Spinal Cord Injury

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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spinal cord injury

Individuals living with a spinal cord injury

No interventions assigned to this group

non spinal cord injury

able-bodied individuals

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Male or Female
* Age between 18 and 60
* German native speaker
* Normal or corrected-to-normal visual acuity


* A diagnosis of traumatic spinal cord injury (SCI)
* Time since injury 12 months or longer
* American Spinal Injury Association Impairment Scale (AIS) grade A, B, C and D

Exclusion Criteria

* Contraindication for magnetic resonance imaging examinations (e.g., cardiac pacemaker etc.)
* Pregnancy
* Diagnosis of other psychiatric or neurological disorders (including tumor in the central nervous system)
* Alcohol and/or drug abuse
* Confirmed diagnosis of traumatic brain injury
* Insufficient hand function (not able to hold a pen due to the restricted motor abilities)
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Swiss Paraplegic Research, Nottwil

NETWORK

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Swiss Paraplegic Research

Nottwil, Canton of Lucerne, Switzerland

Site Status

Countries

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Switzerland

Other Identifiers

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2023-18

Identifier Type: -

Identifier Source: org_study_id

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