Assessment of Neuropathic Pain

NCT ID: NCT02138344

Last Updated: 2025-01-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

600 participants

Study Classification

OBSERVATIONAL

Study Start Date

2006-04-01

Study Completion Date

2024-09-27

Brief Summary

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Development of neuropathic pain is one of the most disabling sequels after spinal cord injury (SCI) and in peripheral nerve diseases. The functionality of the pain pathway in humans as well as its plastic changes following SCI can be assessed in vivo by surface electrophysiological recordings and functional magnetic resonance imaging after noxious heat stimulation of the skin. Aims: a) establishing a clinically applicable assessment of the pain pathway and characterizing its changes as a consequence of SCI and in peripheral nerve diseases in an objective manner, b) characterizing plastic changes in the pain pathway in SCI patients with neuropathic pain and in patients with peripheral nerve diseases and relating them to the development of neuropathic pain syndromes.

Detailed Description

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Conditions

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Spinal Cord Injury + Peripheral Nerve Diseases

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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SCI subjects

Chronic and traumatic SCI subjects

No interventions assigned to this group

Healthy control subjects

No interventions assigned to this group

Subjects with peripheral nerve diseases

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Uninjured
* Scord injured subjects
* Subjects with peripheral nerve diseases
* Patients resident in Switzerland

Exclusion Criteria

* Presence of any central psychiatric disorder (that precludes subject from giving informed and voluntary consent)
* For fMRI measurements: "yes" for any item in the MR-risk questionnaire
* Patients resident outside from Switzerland
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Zurich

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Curt, Armin, MD

Zurich, Canton of Zurich, Switzerland

Site Status

Countries

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Switzerland

Other Identifiers

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EK-04/2006 / PB_2016-02051

Identifier Type: -

Identifier Source: org_study_id

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