Representation of the Bladder Innervation Using Diffusion Tensor Imaging Fiber Tracking With MRI

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

10 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-01-31

Study Completion Date

2015-11-30

Brief Summary

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The exact innervation of the bladder and the changes after a spinal cord injury have been not yet been illustrated.

Diffusion tensor imaging with magnetic resonance imaging is a new technique which can be used to visualize single nerve fibers, and thus represent the neural supply of a region in vivo. There are studies in which both the sacral plexus and the lumbar nerve roots have been represented using diffusion tensor imaging. However, there is no study concerning the innervation of the bladder.

The investigators are therefore using diffusion tensor imaging with magnetic resonance imaging to represent the bladder innervation of individuals with neurogenic lower urinary tract dysfunction and individuals with normal bladder function.

Detailed Description

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Conditions

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Spinal Cord Injury Neurogenic Lower Urinary Tract Dysfunction

Study Design

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Study Time Perspective

PROSPECTIVE

Study Groups

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control

individuals with normal bladder function

No interventions assigned to this group

neurogenic bladder

individuals suffering from neurogenic lower urinary tract dysfunction

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* neurogenic lower urinary trat dysfunction
* normal bladder function

Exclusion Criteria

* no signed informed consent
* contraindications for MRI (pace maker, implanted metal, claustrophobia)
* upper or lower urinary tract surgeries
* pregnancy (anamnestic)

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Responsible Party

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Responsibility Role SPONSOR

Locations

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Swiss Paraplegic Centre

Nottwil, Canton of Lucerne, Switzerland

Site Status

Countries

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Switzerland

Other Identifiers

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2013-25

Identifier Type: -

Identifier Source: org_study_id

Representation of the Bladder Innervation Using Diffusion Tensor Imaging Fiber Tracking With MRI - a Pilot Study