Acute Effects of High-intensity Interval Training With Mindfulness-based Recovery on Executive Function in Children

NCT ID: NCT06270589

Last Updated: 2025-04-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-06-15

Study Completion Date

2026-05-31

Brief Summary

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The goal of this randomized cross-over trial is to learn about the effect of a single bout of 20-min mindfulness-based high-intensity interval training (MF-HIIT), MF-only, and HIIT-only in relative to sitting rest on executive function (EF) in 10-12 years old children. The main question it aims to answer are:

Question 1: Whether a single bout of 20-min MF-HIIT has larger beneficial effect on EF performance than that following a 20-min session of MF-only and HIIT-only in relative to the sitting rest

Question 2: Whether a single bout of 20-min MF-HIIT has a larger beneficial effect on brain functioning, as measured by the N2 and P3 components of event-related potential (ER) during EF performance than that following a 20-min session of MF-only and HIIT-only in relative to the sitting rest

Participants will visit the laboratory on 5 separate days (\> 2-day washout between days) in which they have not previously participated in structured physical activities.

Participants will complete the testing and/or receive treatments below:

Day 1:

* Kaufman Brief Intelligence Test (KBIT) to assess intelligence quotient
* Treadmill-based exercise test to measure cardiorespiratory fitness (maximum oxygen consumption)

Days 2-5

* Each day, participants will complete each of the four intervention conditions (MF-HIIT, MF-only, HIIT-only, sitting)
* Participants' heart rate and self-reported affect and rating of physical exertion will be measured
* Participants will complete a modified flanker task and a task-switching task to assess inhibitory control and cognitive flexibility
* Participants will wear an EEG cap to measure the N2 and P3 components of the event-related potential during the inhibitory control and cognitive flexibility performance

Researcher will compare the cognitive outcome measures following the MF-HIIT, MF-only, and HIIT-only conditions with the sitting condition to see if MF and HIIT has beneficial effects on children's EF.

Further, researcher will compare the cognitive outcome measures following the MF-HIIT compared with MF-only and HIIT-only conditions to see if combining MF with HIIT has greater beneficial effects on children's EF than MF and HIIT alone.

Detailed Description

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Conditions

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Healthy Volunteers

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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A Single Bout Of Mindful High-Intensity Interval Training (Mindful HIIT)

Group Type EXPERIMENTAL

MF-HIIT

Intervention Type BEHAVIORAL

A single bout of 20-min MF-HIIT protocol delivered through a motor-driven treadmill. The protocol will start with a 1.5-min warm-up, then a 16.5-min main exercise (6 x 90s exercise intervals separated by 5 x 90s mindful intervals), and finally a 2-min cool-down.

A Single Bout Of High-Intensity Interval Training (HIIT)

Group Type ACTIVE_COMPARATOR

HIIT-only

Intervention Type BEHAVIORAL

A single bout of 20-min HIIT protocol delivered through a motor-driven treadmill. The protocol will start with a 1.5-min warm-up, then a 16.5-min main exercise (6 x 90s exercise intervals separated by 5 x 90s rest intervals), and finally a 2-min cool-down.

A Single Bout Of Mindfulness

Group Type ACTIVE_COMPARATOR

MF-only

Intervention Type BEHAVIORAL

A single bout of 20-min intervention mindfulness intervention that includes 5 x 90s mindful intervals separated by sitting rest

A Single Bout Of Sitting Rest

Group Type OTHER

Sitting rest

Intervention Type BEHAVIORAL

Participants will sit in a comfortable chair, placed on the treadmill, while watching a HIIT video without mindfulness instructions for 20 minutes.

Interventions

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MF-HIIT

A single bout of 20-min MF-HIIT protocol delivered through a motor-driven treadmill. The protocol will start with a 1.5-min warm-up, then a 16.5-min main exercise (6 x 90s exercise intervals separated by 5 x 90s mindful intervals), and finally a 2-min cool-down.

Intervention Type BEHAVIORAL

MF-only

A single bout of 20-min intervention mindfulness intervention that includes 5 x 90s mindful intervals separated by sitting rest

Intervention Type BEHAVIORAL

HIIT-only

A single bout of 20-min HIIT protocol delivered through a motor-driven treadmill. The protocol will start with a 1.5-min warm-up, then a 16.5-min main exercise (6 x 90s exercise intervals separated by 5 x 90s rest intervals), and finally a 2-min cool-down.

Intervention Type BEHAVIORAL

Sitting rest

Participants will sit in a comfortable chair, placed on the treadmill, while watching a HIIT video without mindfulness instructions for 20 minutes.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Age between 10-12 years old
* Intelligence Quotient ≥ 85
* Capable of performing exercise based on pre-participation health screening
* No formal diagnosis of cognitive disorders (e.g., attention deficit hyperactivity disorder) and neurological diseases (e.g., epilepsy)

Exclusion Criteria

* Age outside of the range of 10-12 years old
* Intelligence Quotient \< 85
* No capable of performing exercise based on pre-participation health screening
* Has formal diagnosis of cognitive disorders (e.g., attention deficit hyperactivity disorder) and neurological diseases (e.g., epilepsy)
Minimum Eligible Age

10 Years

Maximum Eligible Age

12 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Oregon

OTHER

Sponsor Role collaborator

Purdue University

OTHER

Sponsor Role lead

Responsible Party

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Shih-Chun Kao

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Lambert, 800 West Stadium Avenue

West Lafayette, Indiana, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Shih-Chun Kao, PhD

Role: CONTACT

765-496-2213

Facility Contacts

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Shih-Chun Kao, PhD

Role: primary

765-496-2213

Other Identifiers

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IRB-2023-1684

Identifier Type: -

Identifier Source: org_study_id

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